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Cancer Weekly

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Brain Cancer



Anti-angiogenic therapy in pediatric neuro-oncology discussed



February 14th, 2006

Anti-angiogenic therapy in pediatric neuro-oncology was discussed.

"In order to grow, tissues require additional nutrients and oxygen as well as removal of waste products. Tumors achieve this by up-regulating angiogenic cytokines and/or down-regulating natural inhibitory proteins that allow neovascularization to proceed," researchers in the United States reported.

"Brain tumors continue to account for significant morbidity and mortality, in spite of significant advances in neurosurgical and radiation techniques and new chemotherapy combinations. As such, there is a real and immediate need for novel biologic therapies that can target these tumors. A...


Source: Cancer Weekly (2006-02-14)

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