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Cancer Weekly

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Colon Cancer



Use of artepillin C helps prevent colon cancer



February 14th, 2006

Administration of Artepillin C may prevent colon cancer.

According to a study from Japan, "Potential chemopreventive agents exist in foods. Artepillin C in Brazilian propolis was investigated for its effects on colon carcinogenesis."

"We had found that artepillin C was a bioavailable antioxidant, which could be incorporated into intestinal Caco-2 and hepatic HepG2 cells without any conjugation and inhibited the oxidation of intracellular DNA. Artepillin C was then added to human colon cancer WiDr cells. It dose-dependently inhibited cell growth, inducing G(0)/G(1) arrest. The events involved a decrease in the kinase activity of a complex of...


Source: Cancer Weekly (2006-02-14)

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