Cancer Weekly
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Breast Cancer
Role of autoimmunity in breast cancer has broad implications in therapy target discovery
February 14th, 2006
The role of autoimmunity in breast cancer has broad implications for the discovery of molecular targets for drug therapy. "A plethora of promising breast cancer-associated autoantigens have been cloned by immunoscreening cDNA [complementary deoxyribonucleic acid] expression libraries with breast cancer sera or identified using proteomics, yet no biomarkers, whether individual autoantigens or panels of antigens developed using antibody-based methods, have been validated and incorporated to routine oncologic practice for the early diagnosis of breast cancer. Recently, the addition of genomics, proteomics, and high-throughput technology to traditional immunological...
Source: Cancer Weekly (2006-02-14)
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