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Colorectal Cancer

Somatostatin receptor subtype 2 expression used to prognosticate colorectal cancer

Published in Cancer Weekly, February 21st, 2006

Somatostatin receptor subtype 2 (sst2) expression could be used to prognosticate colorectal cancer.

According to recent research from Italy, "The clinical relevance of the sst2 is well defined in neuroendocrine tumors but it is still a matter of debate whether its expression may have a role also in other tumors not arising from the neuroectoderm."

"We investigated the prognostic value of the expression levels of sst2 mRNA in a consistent group of patients affected by colorectal cancer. Survival analysis of cancer-related death showed that patients with a high sst2 mRNA expression had an unfavorable outcome (p=.037) and a significantly shorter...

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