Gastric Cancer

Biweekly PELF chemotherapy regimen deemed feasible in advanced gastric cancer

Published in Cancer Weekly, February 21st, 2006

Biweekly chemotherapy with cisplatin, epirubicin, folinic acid and 5-fluororacil (PELF) continuous infusion plus G-CSF was deemed feasible in gastric cancer.

"It has been demonstrated that the 3-weekly PELF regimen is superior to FAM and FAMTX in advanced gastric cancer. The aim of this multicentric phase II study was to evaluate the efficacy and tolerability of a PELF regimen, given every 2 weeks as a first-line therapy in patients with unresectable or metastatic gastric carcinoma," researchers in Italy reported.

"Fifty-nine patients were treated with the following schedule: cisplatin (40 mg/m², day 1), epirubicin (30 mg/m²,...

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Source: Cancer Weekly (2006-02-21)

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