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Bladder Cancer

Polymorphism in hGPX1 gene may be used as marker for bladder cancer recurrence

Published in Cancer Weekly, February 28th, 2006

Genetic polymorphism in the human glutathione peroxidase 1 (hGPX1) gene may serve as a molecular marker for monitoring bladder cancer recurrence.

"[The study's aim was] to investigate the potential of genetic polymorphism (Pro198Leu) in the hGPX1 gene as a biologic marker predictive of bladder cancer recurrence. Given the high propensity for superficial bladder cancer recurrence, biologic markers that are predictive of recurrence may provide additional helpful information in bladder cancer treatment," investigators in the United States reported.

"To date, few valuable molecular markers have been closely associated with bladder cancer recurrence. In...

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