Bladder Cancer
Expression of E-cadherin and alpha-, beta-, gamma-catenins in bladder cancer analyzed
Published in Cancer Weekly, March 7th, 2006
According to recent research published in the American Journal of Clinical Pathology, "Loss of intercellular adhesion facilitates tumor invasion. To clarify the relation between altered expression of cell adhesion molecules and progression of T1 superficial bladder tumors, 101 cases (71 T1 tumors, 30 T2/T3 tumors) were examined immunohistochemically for E-cadherin and alpha-, beta-, and gamma-catenins."
"A highly significant correlation was observed between the decreased expression of all molecules and increased TNM stage (p<.001). Univariate...
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Source: Cancer Weekly (2006-03-07)
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