Glioma Vaccine
EGFRvIII-derived CTL epitopes restricted by HLA A0201 are identified for glioma immunotherapy
Published in Cancer Weekly, March 7th, 2006
According to recent research published in the Journal of Neuro-Oncology, "The type III variant of the epidermal growth factor receptor (EGFRvIII) mutation is present in 20-25% of patients with glioblastoma multiforme (GBM). EGFRvIII is not expressed in normal tissue and is therefore a suitable candidate antigen for dendritic cell (DC) based immunotherapy of GBM."
An-hua Wu and colleagues at the University of Minnesota and University of California-San Diego wrote, "To identify the antigenic epitopes that may serve...
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Source: Cancer Weekly (2006-03-07)
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