Lung Cancer
A GSTP1 polymorphism may be linked to survival in advanced non-small cell lung carcinoma
Published in Cancer Weekly, March 7th, 2006
According to recent research published in the journal Cancer, "GSTP1 is a detoxification enzyme with substrate specificity for both exogenous carcinogens and chemotherapy agents. Genetic polymorphisms of GSTP1 exon 5 (Ile105Val) and exon 6 (Ala114Val) appear to reduce this enzyme's activity."
"Previously, the authors reported that the exon 6 variant was associated with an increased risk of lung carcinoma, particularly among men, younger patients, and ever smokers. In this...
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Source: Cancer Weekly (2006-03-07)
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