Melanoma
Genetic vaccination with synthetic mRNA induces anti-melanoma immunity
Published in Cancer Weekly, March 14th, 2006
"RNA-based genetic immunization represents an alternative novel strategy for antigen-specific cancer vaccines. In the present paper we investigate the use of synthetic messenger RNA in an experimental melanoma model," wrote J. Steitz and colleagues, University of Bonn.
"We show that gene gun-based immunization using synthetic RNA mediates gene expression in the epidermis and effectively induces antigen-specific cellular and humoral immunity in mice in vivo."
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Source: Cancer Weekly (2006-03-14)
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