Cancer Weekly

Breast Cancer - MCF-7 breast cancer cell growth inhibited by Antrodia camphorata

Colorectal Cancer - Colorectal cancer linked to aberrant promoter methylation of multiple genes

Leukemia - Adult acute megakaryocytic leukemia confirmed to have poor prognosis

Lung Cancer - Lung cancer suppressed by SC-560

Ovarian Cancer - Ovarian cancer prognosis predicted by glutathione S-transferase polymorphisms

Adenomas - DNA methylation patterns of adenomas studied

Adverse Drug Reaction - Oxaliplatin hypersensitivity reactions studied

Ampullary Cancer - Clinicopathologic features of ampullary carcinoma without jaundice evaluated

Anemia Therapy - Darbepoetin alfa saves costs and reduces number of office visits for treatment-related anemia

Angiology - Tumor angiogenesis flourishes in models with TIMP-3 gene deficiency

Antibacterial Agents - Antibiotic use during last days of life in cancer patients analyzed

Apoptosis - Antimonial compounds may work by disrupting thiol homeostasis

Apoptosis - Cyclin D1 overexpression induces apoptosis resistance linked to carcinoma BCL-2

Apoptosis - Retinoblastoma plays a role in survival of Abl-dependent human tumor cells

Assisted Pregnancy - Fertility preservation through ovarian tissue banking may improve pregnancy chances

Asthma & Cancer - Older asthmatics have increased cancer risk

Basal Cell Cancer - Clinical features of basal cell carcinoma in Turkish patients analyzed

Basal Cell Cancer - Referral of excised caruncular lesions for pathological examination recommended

Bile Duct Carcinoma - Imaging features of early bile duct carcinoma identified

Biliary Tract Carcinoma - Biliary tract carcinoma treated by chemoradiation

Bladder Cancer - Cytology of ileal conduit urine bladder cancer studied

Bladder Cancer - Use of bladder tumor markers in management of bladder cancer patients discussed

Brain Cancer - Brain tumors treated by hypofractionated conventional conformation radiotherapy

Brain Cancer - Glioma invasion is stimulated by angiopoietin 2 induction of matrix enzymes

Brain Metastases - Brain metastases clinical predictors identified

Breast Cancer - Breast cancer drug, derived from botanical extract, could treat aggressive breast cancer

Breast Cancer - Breast cancer found associated with steroid receptor RNA activator protein expression

Breast Cancer - Breast cancer linked to expression of autocrine motility factor

Breast Cancer - Breast cancer mortality is associated with region, race, and socioeconomic status

Breast Cancer - Breast cancer patients show preference for oral hormone therapy vs. monthly injections

Breast Cancer - Breast cancer patients' responses to radiotherapy studied

Breast Cancer - Breast cancer risk may be reduced by vigorous recreational activity

Breast Cancer - Breast cancer treated by possible antimetastatic formylated hexapeptide ligand

Breast Cancer - Breast cancer treated with combination of oral vinorelbine and capecitabine

Breast Cancer - Breast carcinoma cells receive support from vascular endothelial growth factor-D

Breast Cancer - Elderly patients with metastatic breast cancer should be included in prospective trials

Breast Cancer - HER-2/neu expression used to prognosticate primary breast cancer

Breast Cancer - Hirsutenone inhibits COX-2 and MMP-9 upregulation in mammary epithelial cells

Breast Cancer - Korean breast cancer patterns reflect those of Western countries

Breast Cancer - M. D. Anderson Cancer Center to investigate chemokine antagonist for breast cancer

Breast Cancer - Metastatic breast cancer treated by combination of pemetrexed and gemcitabine

Breast Cancer - New findings in breast cancer described

Breast Cancer - Probe for new breast biopsy device launched by SenoRx Inc.

Breast Cancer - Recent findings in breast cancer provide new insights

Breast Cancer - Research add new data to breast cancer body of knowledge

Breast Cancer - Roche pursues European market approval of Herceptin for early-stage HER2-positive breast cancer

Breast Cancer - Role of ductal lavage in predicting breast lesions investigated

Breast Cancer - Socioeconomic determinants of breast reconstruction analyzed

Breast Cancer Risk Factors - Breast cancer risk prediction from diet quality indices was evaluated

Breast Cancer Screening - Breast tumor size prediction methods were compared for accuracy

Breast Cancer Therapy - Breast cancer risk reduction awareness was evaluated among women from different ethnic groups

Breast Cancer Therapy - Researchers detail new studies and findings in the area of breast cancer therapy

Breast Cancer Therapy - Researchers provide details of new studies and findings in the area of breast cancer therapy

Breast Cancer Therapy - Timing of aromatase inhibitors added to breast cancer therapy affects cost-effectiveness

Breast Cancer Vaccine - Breast cancer prognostic information is aided by monocyte chemotactic protein-1

Breast Cancer Vaccine - Breast cancer tumors frequently express cancer testis genes

Breast Cancer Vaccine - IL-12 and GM-CSF microsphere therapy eradicates tumors but does not provide long-term cure

Breast Implants - Breast implants were not shown to increase long-term breast cancer risk

Bronchioloalveolar Cancer - Bronchioloalveolar carcinoma management discussed

Business & Finance - Biovest International reports quarterly loss of $0.04 per share

Business & Finance - Clarient reports fourth-quarter net revenue of $6.0 million

Business & Finance - Coley Pharmaceutical Group reports Q4 revenue of $5.4 million

Cancer Coping - Psychological impact of discussing poor prognosis to cancer patients examined

Cancer Gene Therapy - PEG10 is a c-MYC target gene in cancer cells

Cancer Gene Therapy - Peroxiredoxin I expression affects lung tumor growth and radiosensitivity

Cancer Gene Therapy - RNA interference induces cell cycle arrest and apoptosis in breast carcinoma cells

Cancer Research - Morphotek announces U.S. FDA acceptance of MORAb-009 IND

Cancer Therapy - 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase proposed as cancer therapy target

Cancer Therapy - Advanced pancreatic cancer celiac axis infusion and microembolization improves resection

Cancer Therapy - Advaxis' listeria cancer vaccine receives regulatory approval for phase I/II testing

Cancer Therapy - Aegera initiates third trial for AEG35156 for patients with acute myeloid leukemia

Cancer Therapy - Antifungal treatment for patients on chemotherapy deemed cost-effective

Cancer Therapy - Antimetastasis data to be presented by Chemokine at meeting

Cancer Therapy - Antisense therapy is well tolerated in patients with metastatic colorectal cancer

Cancer Therapy - Bioenvision's clofarabine receives positive opinion from European Medicines Agency

Cancer Therapy - Bone metastasis is prevented by a selective cyclooxygenase-2 inhibitor

Cancer Therapy - Brain cancer patients living longer after DCVax-Brain personalized vaccine therapy

Cancer Therapy - Cancer cell growth inhibited by digitoxin

Cancer Therapy - Cancer patients' opinions concerning post-treatment follow-up surveyed

Cancer Therapy - Cisplatin functions as ARF mimic

Cancer Therapy - High-dose cyclophosphamide may be unnecessary therapy for lymphoid malignancies

Cancer Therapy - Multikine treatment increases survival in head and neck cancer patients

Cancer Therapy - New findings in cancer therapy described

Cancer Therapy - New findings in the area of cancer therapy described

Cancer Therapy - Phenylcarbazoles display antitumor properties

Cancer Therapy - Researchers detail new studies and findings in the area of cancer therapy

Cancer Therapy - Researchers' data advance cancer therapy research

Cancer Therapy - Researchers' findings advance cancer therapy research

Cancer Therapy - Studies advance knowledge in cancer therapy research

Cancer Therapy - Studies describe new findings in cancer therapy research

Cancer Therapy - Sutent approved for use in U.S. in kidney cancer, gastrointestinal stromal tumors

Cancer Therapy - Thymosin beta 4 determines fibroblast transformation and invasiveness

Cancer Therapy - Transfer of EBV-specific polyclonal T-cell lines may be helpful in patients with lymphoma

Cancer Therapy - Tumor angiogenesis and growth proliferate in minimal disease models given TNP-470

Cancer Treatments - ProStrakan receives U.S. FDA approval of IND for patch to treat side effects of chemotherapy

Cancer Vaccine - Antitumor activity in human lymphocytes is triggered by vaccine

Cancer Vaccine - Chaperone-rich cell lysates are good antigen source for anticancer vaccines

Cancer Vaccine - Contract arrangement announced for cGMP production of GRNVAC1 for clinical trials

Cancer Vaccine - For gene therapy of cholangiocarcinoma, tumor-specific promoters have been identified

Cancer Vaccine - Mouse hepatitis coronavirus is targeted to human epidermal growth factor receptor

Cancer Vaccine - NY-ESO-1 epitopes recognized by CD4+ T cells and presented by HLA-DQ B1 03011 have been identified

Cancer Vaccine - SOCS1 restricts dendritic cells' ability to induce antitumor immunity

Cancer Vaccine - Vaccine induces response against carcinoembryonic antigen in patients with metastases

Cancer Vaccines - Recent findings illuminate research in cancer vaccines

Cancer Vaccines - Researchers report details of new studies and findings in the area of cancer vaccines

Carcinogenesis - Antitumor resistance activation in mice was focus of research

Carotid Body Tumor - Current concepts for surgical management of carotid body tumor discussed

Central Nervous System Lymphoma - Central nervous system lymphoma survival improved with combined-modality therapy

Central Nervous System Tumors - Early rehabilitation of pediatric patients with central nervous system tumors advised

Cervical Cancer - Cervical cancer growth is inhibited by the angiogenesis modulator NOL7

Cervical Cancer - Cervical cancer screening may be enhanced by Digital Cervicography test

Cervical Cancer - Cervical cancer therapy with cisplatin appears comparable to other agents in same setting

Cervical Cancer - Drug-delivery system for cervical cancer lesions licensed to CytoCore

Cervical Cancer - Human papillomavirus tissue affinity may contribute to carcinogenic potential

Cervical Cancer - Partial trachelectomy may offer viable treatment for women with cervical lesions

Cervical Cancer - Progression of cervical neoplasia linked to decreased galectin-3 expression

Cervical Cancer Screening - Reports describe recent advances in cervical cancer screening research

Cervical Cancer Vaccine - Human papillomavirus-16 vaccine prevents cervical intraepithelial neoplasia

Chemotherapy - New findings in chemotherapy described

Cirrhosis - Recurrence of hepatocellular carcinoma after liver resection evaluated

Clinical Trials - Celsion signs Agreement with Fast Track Systems and CROCAS PBT

Clinical Trials - Clinical study of small molecule Telintra tablet for myelodysplastic syndrome initiated

Clinical Trials - Norwood Abbey commences phase II trial of Lupron Depot in autologous bone marrow transplants

Collaborations - New U.S. federal health initiative to improve cancer therapy

Collaborations - ProBioGen, Affimed continue clinical materials collaboration

Collaborations - Research collaboration to develop micro-RNA related therapies for liver cancer announced

Collaborations - Rexahn and University of Maryland Nanomedicine Center to develop cancer and CNS therapies

Colon Cancer - 9-aminocamptothecin-HPMA copolymer conjugates developed for colon cancer drug delivery

Colon Cancer - Clinical trial Buddy Program offered by Colon Cancer Alliance

Colon Cancer - Tissue block types should be scanned for venous invasion in colorectal carcinoma

Colorectal Adenocarcinomas - Colorectal carcinoma tumor-associated stroma has a metabolic survival role

Colorectal Adenocarcinomas - Molecular features of signet ring cell cancer and mucinous cancer compared

Colorectal Cancer - Clinical utility of standardized uptake value on FDG-PET in colorectal cancer assessed

Colorectal Cancer - Colorectal cancer metastasis is hampered by antibodies targeting VEGF

Colorectal Cancer - Colorectal cancer patients preferred oral to intravenous therapy

Colorectal Cancer - Expression of p53 mutations in colorectal cancer cell lines examined

Colorectal Cancer - Interval between colorectal cancer screenings could be expanded beyond 5 years

Colorectal Cancer - Link between polymorphisms and environmental factors in colorectal cancer risk discussed

Colorectal Cancer - Metastatic colorectal cancer may be manifested by an ovarian mass

Complementary & Alternative Medicine - 5-OH-isoflavone consumption is of no direct cytotoxic risk to the human vascular endothelium

Complementary & Alternative Medicine - Degraded lambda-carrageenan could add antitumor activities of 5-Fu

Complementary & Alternative Medicine - New class of CDK2 inhibitors developed

Complementary & Alternative Medicine - Protective mechanisms of omega-3 long-chain polyunsaturated fatty acids are reviewed

DNA Vaccine - Interleukin-18 enhances Th1 immunity and tumor protection of a DNA vaccine

Diabetes Control - OSI Pharmaceuticals initiates phase IIa trial for glycogen phosphorylase inhibitor, PSN357

Diagnostics - Adenocarcinoma angiogenesis is identified by a double immunolabeling technique

Diagnostics - Dentists' device for detection of oral pre-cancer lesions introduced

Diagnostics - EBV-related smooth muscle tumors histologically distinct from classic soft tissue SMTs

Diagnostics - Findings describe new data in diagnostics research

Diagnostics - New findings in the area of diagnostics described

Diagnostics - Reports describe recent advances in diagnostics research

Diagnostics - Signet, AsymmetRx sign distribution agreement for prostate cancer diagnostic test rights

Diagnostics - Soft tissue sarcoma tissue microarray immunostaining provides valuable prognostic information

Diet & Nutrition - No clear differences in cancer rates among vegetarians and non-vegetarians found

Diet & Nutrition - Nutrition council finds WHI study outcomes inconsistent for calcium, vitamin D supplementation

Diet & Nutrition - Studies describe new findings in diet & nutrition research

Diet & Nutrition - Vegetable-derived isothiocyanates examined for anti-proliferative activity

Disease Associations - Cancer risk among patients with multiple sclerosis assessed

Disease Associations - Incidence of venous thromboembolism studied in patients hospitalized with cancer

Drug Development - Access Pharmaceuticals initiates a new AP5346 study in patients with head and neck cancer

Drug Development - BioVex begins dosing of patients in phase II trial of OncoVEXGMCSF

Drug Development - Biovest submits amendment request to U.S. FDA for BiovaxID personalized anticancer vaccine

Drug Development - Combination of porphyrins and DNA-alkylation agents described

Drug Development - Dendrons with spermine surface groups are building blocks for nonviral vectors

Drug Development - Erbitux indication extended to include head and neck cancer

Drug Development - Fluorescent phorboxazole A analog developed

Drug Development - Pharmacogenomics added to development of new marine-derived anticancer agents

Drug Development - Potent inhibitor of antiapoptotic protein Bcl-x(L) discovered

Drug Development - Recruitment interrupted for AEterna Zentaris phase III trial of Neovastat in lung cancer

Drug Development - Toxicology studies with MPI Research begun by Diffusion Pharmaceuticals, LLC

Drug Development - Two novel, small-molecule inhibitors of DNA methylation discovered

Drug Development - U.S. FDA grants orphan drug status to Coramsine for malignant melanoma

Drug Development - Vaccinia virus Ankara multiplies in rat IEC-6 cells

Ebola Vaccine - Ebola vaccine with Vical technology produces immune responses in trial volunteers

Endometrial Cancer - Endometrial cancer therapy may be enhanced with adjuvant whole abdominal radiotherapy

Endometrial Cancer - Researchers report details of new studies and findings in the area of endometrial cancer

Endometrial Carcinoma - Endometrial carcinoma progression is associated with HOXA10 deregulation

Esophageal Cancer - Two-year survival from esophageal cancer predicted with FDG-PET upstaging

Facilities - Cambridge, Massachusetts new office site for Gene Network

Fibroids - Fibroids have low recurrence rates after laparoscopic uterine artery occlusion

Finance - Baxter's board authorizes $1.5B share repurchase program

Finance - Cel-Sci raises $1M in new equity

Finance - Cell Genesys reports net income of $19.1 million

Finance - Exelixis announces Q4 losses of $24.5 million

Finance - Mesothelioma Applied Research Foundation awards nearly $1 million for research aimed at a cure

Finance - Monogram announces revenue of $12.7 million for the fourth quarter