Uveal Melanoma

Extracellular matrix proteins in uveal melanoma reconstructed in 3D

Published in Cancer Weekly, March 21st, 2006

Extracellular matrix proteins in uveal melanoma could be reconstructed in 3D.

According to recent research from the United States, "The distribution of looping patterns of laminin in uveal melanomas and other tumors has been associated with adverse outcome. Moreover, these patterns are generated by highly invasive tumor cells through the process of vasculogenic mimicry and are not therefore blood vessels. Nevertheless, these extravascular matrix patterns conduct plasma. The three-dimensional (3D) configuration of these laminin-rich patterns compared with blood vessels has been the subject of speculation and intensive investigation."

"We have...

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Source: Cancer Weekly (2006-03-21)

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