Lung Cancer

Lung cancer suppressed by SC-560

Published in Cancer Weekly, March 21st, 2006

Lung cancer could be suppressed by 5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole (SC-560).

"SC-560 is a structural analog of celecoxib. Recent studies suggested that SC-560 inhibits the in vivo proliferation of colon and breast cancer cells to an extent similar to that observed in celecoxib, and that SC-560 exerts their growth inhibitory effects in a cyclooxygenase-independent manner. In the current study, we sought to investigate the mechanism by which SC-560 inhibits the growth of human lung cancer cells," scientists in South Korea reported.

"SC-560 more potently inhibited the growth of human A549, H460, and H358 lung cancer cell...

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Source: Cancer Weekly (2006-03-21)

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