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Drug Development

ArQule initiates toxicology studies of RQ 171

Published in Cancer Weekly, March 28th, 2006

ArQule, Inc., (ARQL) announced the initiation of GLP toxicology studies with ARQ 171, the second compound generated through the company's ARQ-550RP Activated Checkpoint Therapy (ACT) program, under its agreement with Roche.

"With the initiation of these studies, we are taking an important step toward the clinic with a second compound from our E2F1 checkpoint pathway program, based on our alliance with Roche," said Stephen A. Hill, president and chief executive officer of ArQule. "If data from these studies with ARQ 171 are supportive, the next step in the development process for ARQ 171 will be the filing of an investigational new drug application."

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