Cancer Weekly

Cancer Therapy - Arctigenin identified as an antitumor agent

Environmental Health - Cancer incidence linked to air emissions of volatile organic compounds

Melanoma - Spitzoid melanoma identified as distinct subtype of melanoma

Non-Hodgkin Lymphoma - Detection of bone marrow lesions improved by ferumoxtran-10-enhanced MR imaging

Ovarian Cancer - Outcomes after ovarian cancer resection not linked to hospital and surgeon procedure volumes

Acute Myeloid Leukemia - Acute myeloid leukemia risk associated with treatments for Hodgkin lymphoma estimated

Adenocarcinomas - Long-term results of primary adenocarcinoma of urinary bladder reviewed

Adenomas - Adenoma diagnosis by CT alone may lead to misdiagnosis

Adrenocortical Cancer - Adrenocortical cancer treated by mitotane

Adverse Drug Reaction - Incidence of ischemic stroke post-chemotherapy reviewed

Adverse Drug Reaction - KS aggravated by rituximab when used to treat HIV-related multicentric Castleman disease

Allergy & Immunology - Modified Langerhans-type dendritic cells express full-length stimulatory antigen

Anemia & Cancer - Researchers find ways to ease cancer treatment

Angiology - Shamblin classification requires modification to reflect morbidity of carotid body tumors

Apoptosis - Cells' commit suicide on signal

Apoptosis - Hepatoma cell apoptosis is enhanced by interferon-alpha

Apoptosis - Modified endothelial cells initiate vascular endothelial growth factor-driven apoptosis

Arthritis & Cancer - New insights into the link between rheumatoid arthritis and cancer

Astrocytomas - Speech deficits indicated as sequelae of transient cerebellar mutism

Awards - Pennsylvania Breast Cancer Coalition is finalist for 2006 Nonprofit Innovation Awards

Benign Prostatic Hyperplasia - Treatment guidelines for benign prostatic hyperplasia overviewed

Biotechnology - Diosynth enters long-term commercial supply agreement with Dendreon Corp.

Bladder Cancer - Bladder tumor grading performed via advanced soft computing diagnosis method

Bladder Cancer - Findings in bladder cancer provide new insights

Bladder Cancer - Muscle-invasive bladder carcinoma treated by adjuvant chemotherapy

Bladder Cancer - No treatment urgency indicated in patients with low-grade papillary tumors

Bladder Cancer - Perioperative mortality from radical cystectomy for bladder cancer analyzed

Brain Cancer - Inversion recovery MR sequences used to assist in specifying surgical boundaries

Brain Cancer - Neurologists recommend MRIs for early detection of brain metastases in lung and breast cancer

Breast Cancer - Ability of MRI and MRS to predict tumor response to chemotherapy in breast cancer patients assessed

Breast Cancer - Accuracy of blood test for breast cancer to be subject of clinical study by Biomarker

Breast Cancer - Aromatase inhibitor therapy trials are promising but long-term effects are still uncertain

Breast Cancer - Aromatase inhibitors for adjuvant breast cancer therapy may improve long-term survival

Breast Cancer - Breast cancer angiogenesis may flourish because of estrogen receptor variants

Breast Cancer - Breast cancer gene profiling is facilitated by Raf-1 protein kinase inhibition

Breast Cancer - Breast cancer in older women may be linked to estrogen-metabolizing enzyme pattern

Breast Cancer - Breast cancer linked to allelic imbalance at 11q23-q24 chromosome

Breast Cancer - Breast cancer patients' trust in familial input for decision-making differs by ethnicity

Breast Cancer - Breast cancer survivors were interviewed regarding severity and prevalence of menopausal symptoms

Breast Cancer - Breast cancer treated by gemcitabine in combination with vinorelbine

Breast Cancer - Breast cancer treated with low doses of alpha particle irradiation

Breast Cancer - Breast radiation with intensity-modulated radiation therapy reduces skin toxicity

Breast Cancer - Breast size affected dose delivered by intensity-modulated radiation therapy

Breast Cancer - Cell-penetrating peptide used to overcome methotrexate resistance in breast cancer cells

Breast Cancer - Effects of alcohol on breast cancer cell migration analyzed

Breast Cancer - Efficiency of observers to discriminate malignant from benign breast lesions assessed

Breast Cancer - Fatigue in long-term breast carcinoma survivors investigated

Breast Cancer - Her-2 neu positive older women with breast cancer may require more aggressive therapy

Breast Cancer - Herceptin sensitizes ErbB2-overexpressing cells to apoptosis

Breast Cancer - Incidence of BRCA1/BRCA2 mutations in breast cancer patients varies by ethnicity

Breast Cancer - Potential use of COX inhibitors in breast cancer evaluated

Breast Cancer - Presence of inflammatory response indicated poor outcome in breast cancer patients

Breast Cancer - Research in breast cancer provides new insights

Breast Cancer - Researchers provide details of new studies and findings in the area of breast cancer

Breast Cancer - Some breast lesions benign on needle biopsy show cancer when removed

Breast Cancer - Tumor identification may be aided by perioperative magnetic resonance imaging

Breast Cancer - Unplanned readmission within 30 days predicted adverse outcome in breast cancer surgery

Breast Cancer Therapy - New findings in breast cancer therapy described

Business Update - CyberKnife System use for extracranial tumors is growing, says Accuray

Business Update - EDAP reports significant success in the United Kingdom

Business Update - Emageon signs agreement with H. Lee Moffitt Cancer Center

Cancer Development - Cytoskeleton network gene abnormalities might trigger oral leukoplakia

Cancer Diagnostics - Likelihood of urban primary care physicians to recommend colonoscopy studied

Cancer Gene Therapy - BRCA1 and BRCA2 are molecular targets in breast and prostate cancer cells

Cancer Gene Therapy - Combination gene therapy is effective for pancreatic adenocarcinoma

Cancer Gene Therapy - Findings in cancer gene therapy provide new insights

Cancer Gene Therapy - Gastric cancer treatment aided by suicide gene therapy combined with hyperthermia

Cancer Gene Therapy - Methyltransferase depletion therapy mediates growth arrest and apoptosis

Cancer Gene Therapy - RNA interference inhibits the proliferation of pediatric hepatic tumors

Cancer Gene Therapy - Triple anti-tumor gene transfer inhibits growth in glioblastoma cells

Cancer Gene Therapy - Tumor cells can be sensitized to chemotherapeutic agents or TRAIL

Cancer Immunotherapy - Kinase insert domain-containing receptor draws cytotoxic cells to tumor vessels

Cancer Incidence - Frequency of additional cancers in patients with splenic marginal zone lymphoma assessed

Cancer Metastasis - Invasive breast cancer harbors enzyme gene polymorphisms

Cancer Research - Compugen leads consortium to model cancer-related kinase pathway

Cancer Research - ECV304 human bladder cancer cocultures model tumor angiogenesis

Cancer Research - Micromet study provides insight into dosing requirements for anticancer antibodies

Cancer Research - Promising preclinical results from oncolytic virus research using hamster model published

Cancer Risk Factors - Cancer incidence studied in dry cleaning workers in Nordic countries

Cancer Therapy - Advaxis receives approvals to commence study of Listeria vaccine for cervical cancer

Cancer Therapy - Amifostine makes radiation to treat cancer more effective, eases side effects

Cancer Therapy - Anaplastic lymphoma kinase activity is essential for lymphoma cells

Cancer Therapy - Antiangiogenic anginex assaults the cell membrane

Cancer Therapy - Antitumor activity of physalins B and D investigated

Cancer Therapy - Cancer invasion is contained by bone morphogenetic protein-2

Cancer Therapy - CancerVax files IND for anti-angiogenic antibody D93

Cancer Therapy - Cordycepin antitumor effect involves adenosine receptor stimulation

Cancer Therapy - CytoDyn CEO acquires cancer-fighting compound

Cancer Therapy - Disease-free survival following breast cancer remission is improved by new treatment regimen

Cancer Therapy - Effect of combretastatin A-4 phosphate added to fractionated irradiation described

Cancer Therapy - Efficacy of L-carnitine in cancer patients undergoing anticancer therapy studied

Cancer Therapy - Efficacy of antiemetic interventions examined among children receiving chemotherapy

Cancer Therapy - Galloyl pyrrolidine derivatives proposed as potential anti-tumor agents

Cancer Therapy - Hook effect in calcitonin immunoradiometric assays can alter prognosis

Cancer Therapy - Hyperthermia could become a powerful anticancer weapon

Cancer Therapy - Mitochondria proposed as target for cancer therapy

Cancer Therapy - Most patients with lymphoma succumb to infectious complications

Cancer Therapy - New data illuminates research in cancer therapy

Cancer Therapy - New findings in cancer therapy described

Cancer Therapy - New findings in the area of cancer therapy described

Cancer Therapy - New findings in the area of cancer therapy detailed

Cancer Therapy - New research in the area of cancer therapy detailed

Cancer Therapy - Reports add new data to cancer therapy research

Cancer Therapy - Researchers' findings advance cancer therapy research

Cancer Therapy - Researchers' work adds to cancer therapy body of knowledge

Cancer Therapy - Trastuzumab breast cancer therapy efficacy predicted by PTEN activity

Cancer Therapy - Usefulness of gemcitabine as radiosensitizer in undifferentiated tumors examined

Cancer Vaccine - Antitumor immunity is enhanced by DNA vaccine encoding chemokines and prostate-tumor antigens

Cancer Vaccine - Antitumor responses are elicited by low dose of live tumor cells

Cancer Vaccine - Cancer vaccine development is aided by data on tumor antigen processing and presentation

Cancer Vaccine - Chemotherapy-p53 cancer vaccine combination induces small cell lung cancer immune response

Cancer Vaccine - Green fluorescent protein-expressing murine tumor cured by photodynamic therapy

Cancer Vaccine - Leukemia vaccination is the focus of review

Cancer Vaccine - Melanoma-associated CTL response is enhanced by CD4 T cells in transgenic mice

Cancer Vaccine - Method to predict structure of peptides bound to MHC class I has been developed

Cancer Vaccine - Monoclonal antibodies to hepatocyte growth factor show therapeutic potential against tumors

Cancer Vaccine - PAX-FKHR fusion protein breakpoint epitope induces CTL that lyse tumors

Cancer Vaccine - Proteasome-inhibited dendritic cells improve HLA-class I peptide epitope presentation

Cancer Vaccine - Telomerase peptides are immunizing agent in cancer patients

Cancer Vaccine - Tumor immunity is enhanced by canary pox virus expressing melanoma antigen

Cancer Vaccine - Tumor vaccine development is using recognition of tumor glycans by antigen-presenting cells

Cancer Vaccines - Data advance knowledge in cancer vaccines research

Cancer Vaccines - New data illuminates research in cancer vaccines

Cancer Vaccines - Recent findings in cancer vaccines provide new insights

Cancer Vaccines - Reports add new data to cancer vaccines research

Cancer Vaccines - Researchers detail new studies and findings in the area of cancer vaccines

Cancer Vaccines - Studies add new findings to cancer vaccines body of knowledge

Carcinogenesis - Antitumor potential of beef conjugated linoleic acid isomers evaluated

Carcinogenesis - Hepatitis B and C viral interaction may have a role in hepatocellular carcinogenesis

Carcinogenesis - Hydrogen sulfide implicated as a genotoxic agent

Central Nervous System Tumors - Outcomes of central nervous system tumors in pediatric patients reviewed

Cervical Cancer - GlaxoSmithKline submits Cervarix marketing application in the European Union

Cervical Cancer - HPV infection a top risk factor for cervical adenocarcinoma worldwide, study says

Cervical Cancer - Housestaff adherence to cervical cancer screening recommendations surveyed

Chronic Myelogenous Leukemia - Human leukemic cells killed by nuclear entrapment of BCR-ABL

Cleft Lip & Palate - Cleft lip/palate linked to CDH1/E-cadherin mutations in families with gastric cancer

Clinical Trials - Adherex expands phase II ADH-1 trial to include three additional Canadian sites

Clinical Trials - Alizyme reports positive preliminary results of phase IIa trial of ATL-104 for mucositis

Clinical Trials - Barriers to participation in cancer clinical trials identified

Clinical Trials - WEX Pharmaceuticals announces committee recommendation to halt Tectin phase 2b/3 trial

Collaborations - Antisoma to evaluate rain forest anticancer compounds from EcoBiotics

Collaborations - Bradmer completes manufacturing agreement with Laureate Pharma for Neuradiab

Colon Cancer - Colonic lesions diagnosed by elastic scattering spectroscopy

Colon Cancer - Early, frequent colon cancer screenings encouraged for Crohn, ulcerative colitis patients

Colon Cancer - NetWellness premieres new colon cancer information site for consumers

Colorectal Cancer - Chemotherapy given directly to the liver improves survival for patients with colorectal cancer

Colorectal Cancer - Colorectal cancer can be treated with irinotecan, oxaliplatin and raltitrexed

Colorectal Cancer - Colorectal cancer rates do not appear affected by vitamin D and calcium supplements

Colorectal Cancer - Colorectal cancer treated by irinotecan, oxaliplatin, 5-fluorouracil and folinic acid

Colorectal Cancer - Endoscopic procedures and diagnoses not influenced by seasonal variations

Colorectal Cancer - Gilda's Club Worldwide launches art contest to illustrate colorectal cancer survival

Colorectal Cancer - Minimal preparation CT used to detect suspected colorectal cancer in elderly

Colorectal Cancer - Nuclear APC mediates Wnt coregulator exchange

Colorectal Cancer - Venous thromboembolic events linked to breast and colorectal carcinoma diagnoses

Complementary & Alternative Medicine - Angiogenesis and tumor growth can be thwarted by licorice root extract

Cord Blood - Data advance knowledge in cord blood research

DNA Research - Modified oligonucleotides produce efficient and persistent gene silencing

Dermatology - Bradley Pharmaceuticals launches skin cancer public service program

Dermatology - Sun-protective behavioral interventions for young women decrease sunbathing activity

Dermatomyositis - Oral lesions identified as initial manifestation of dermatomyositis with occult malignancy

Desmoplastic Fibromas - Desmoplastic fibroma of the skull described

Diagnostics - Cancer therapy response can be detected by a new gene screening tool

Diagnostics - Immunofluorimetric assay to detect urokinase receptor chemotactic epitope is developed

Diet & Nutrition - Effect of antioxidant vitamins on reducing risk of lung cancer investigated

Diet & Nutrition - Lupin kernel fiber foods improved markers of healthy bowel and colon cancer risk

Diet & Nutrition - Need to motivate fruit and vegetable intake among callers to Cancer Information Service proposed

Drug Delivery - NovaDel announces completion of clinical trials for Zensana oral spray for chemotherapy patients

Drug Development - American Pharmaceutical receives two tentative U.S. FDA approvals for Ondansetron

Drug Development - BiPar Sciences commences phase I trial for BSI-201 in patients with advanced cancer

Drug Development - Findings describe new data in drug development research

Drug Development - Lorus announces publication of studies related to anticancer therapies

Drug Development - Studies describe new findings in drug development research

Drug Development - Tumor angiogenesis may stall when treated with tRNA synthetase fragments

Drug Resistance - New findings in drug resistance described

Endometrial Cancer - Myometrial invasion assessed by sonohysterography may be useful in preoperative staging

Environmental Health - Hospital wastewater found to be genotoxic

Environmental Health - Level of exposure to N-nitrosamines in rubber-manufacturing industry analyzed

Environmental Health - Parental occupational exposure linked to risk of acute lymphoblastic leukemia in offspring

Environmental Health - Volatile organic compounds in photocopy centers linked to cancer in Taiwan

Esophageal Cancer - Chinese esophageal squamous cell carcinoma linked to aberrant RASSF1A gene

Esophageal Cancer - Esophageal cancer progression correlated with reduced PABPC1 expression

Finance - Allos Therapeutics reports loss of $0.10 per share

Finance - Cell Therapeutics reports 2005 fourth-quarter and year-end results; Q4 revenues $1.2M

Finance - Endocare reports 2005 fourth quarter and year-end results, increase in revenues

Finance - EntreMed reports fourth quarter and year-end 2005 financial results

Finance - Favrille announces $45 million financing to support FavId development

Finance - GTC Biotherapeutics reports fourth quarter, year-end 2005 financial results down

Finance - MediGene AG to increase share capital

Finance - Nereus Pharmaceuticals closes second tranche of $42.6 million financing

Finance - Novelos Therapeutics announces $15 million private placement