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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . April 10th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Lung Cancer - Quinuclidinone analogs examined as anti-proliferative agents in lung cancer

Pheochromocytomas - Pheochromocytoma linked to clusterin expression

Prostate Cancer - Prostate cancer linked to 90K/Mac-2 binding protein expression

Rhabdomyosarcomas - Mel-resistant rhabdomyosarcoma cells sensitized to melphalan by TRAIL

Acute Myeloid Leukemia - Acute myeloid leukemia outcome not improved after daunorubicin, cytarabine, and thioguanine therapy

Antisense Technology - Antisense oligonucleotide library validates Eg5 as a drug development target

Apoptosis - An adenovirus mutant induces apoptosis and cell-cycle arrest in tumor cells

Apoptosis - Estrogen induction protects cells from mediated apoptosis

Apoptosis - Myc overexpression and ATM inactivation implicated in tumorigenesis

Apoptosis - Polyphenols purified from the aroeira plant induced apoptosis in DU145 cells

Apoptosis - Role of annexin A5 imaging in cancer treatment and surveillance explored

Apoptosis - Schisandrin B enhanced doxorubicin-induced apoptosis of cancer cells

Apoptosis - Studies add new findings to apoptosis body of knowledge

Artificial Liver - Serum-free cultured hepatocytes propagated and characterized for downstream applications

Aspergillosis Diagnostics - Invasive aspergillosis and mucormycosis rapidly detected by seminested PCR

Astrocytomas - Pilomyxoid astrocytoma diagnosed in a patient with neurofibromatosis

Bioartificial Liver - Bioartificial liver effectively treats fulminant hepatic failure

Bladder Cancer - Bladder cancer mortality in the U.S. influenced by gender and geography

Bladder Cancer - Invasive bladder cancer outcomes defined using oligonucleotide microarrays

Bladder Cancer - Nonmuscle invasive micropapillary bladder carcinoma treated by early cystectomy

Brain Cancer - Brain lesions differentiated by proton magnetic resonance spectroscopic imaging

Brain Cancer - Survival of children with primary brain tumors in England and Wales analyzed

Breast Cancer - Adverse breast tumor profile may not be associated with antibiotic use prior to diagnosis

Breast Cancer - Breast cancer ErbB2 signals ignite a proangiogenic cascade

Breast Cancer - Breast cancer cells display alternative splicing

Breast Cancer - Breast cancer in premenopausal women may be associated with prolactin concentrations

Breast Cancer - Breast cancer patients with ATM gene alteration may develop fibrosis after radiotherapy

Breast Cancer - Breast cancer prognosticated by aberrant expression of 5-lipoxygenase-activating protein

Breast Cancer - Breast cancer response to endocrine therapy prognosticated by changes in proliferation

Breast Cancer - Breast cancer therapy trends show favorable physician response to published guidelines

Breast Cancer - Breast cancer therapy utilizes retrovirus-mediated tk gene

Breast Cancer - Breast cancer treatment disparities may exist due to ethnicity and insurance status

Breast Cancer - Breast carcinoma treatment outcomes were analyzed after neoadjuvant chemotherapy

Breast Cancer - Breast symmetry can be early indicator of breast cancer, say experts

Breast Cancer - Concord grape juice may inhibit formation of breast cancer tumors

Breast Cancer - Findings advance knowledge in breast cancer research

Breast Cancer - Human breast carcinoma survival predicted by ADAMTS8 and ADAMTS15 expression

Breast Cancer - Lower breast cancer survival rates among South Asian women reveals need for outreach

Breast Cancer - Mammography rates underscore important role of healthcare providers

Breast Cancer - Omitting axillary dissection after negative sentinel node biopsy is not contraindicated

Breast Cancer - Possible breast cancer therapy believed to be inhibition of Notch signaling

Breast Cancer - Predicting posttraumatic growth in breast cancer survivors discussed

Breast Cancer - Proliferation of breast cancer measured by Ki67 expression

Breast Cancer - Recent findings illuminate research in breast cancer

Breast Cancer - Reports add new data to breast cancer research

Breast Cancer - Reports advance knowledge in breast cancer research

Breast Cancer - Researchers report details of new studies and findings in the area of breast cancer

Breast Cancer - Researchers' work adds to breast cancer body of knowledge

Breast Cancer - Studies add new findings to breast cancer body of knowledge

Breast Cancer - Trastuzumab plus docetaxel or vinorelbine is effective in certain women with breast cancer

Breast Cancer - Value of prognostic factors to predict risk of death in breast cancer patients waned with time

Business & Finance - Hana Biosciences reports 2005 net loss of $10 million, discusses milestones

Business & Finance - Kosan reports Q4 2005 and year-end financial results, announces corporate restructuring

Business Update - Most laboratories in Ireland adopting Cytyc's Pap test for cervical cancer detection

Business Update - Sequenom launches quantitative methylation and gene expression analysis products

Business Update - Signet announces availability of two new monoclonal antibodies for diagnostic research

Cancer Gene Therapy - Bladder cancer growth is inhibited by an adenovirus expressing dual therapeutic genes

Cancer Gene Therapy - Cervical cancer cell death can be induced by E6 siRNA

Cancer Gene Therapy - Enhanced bladder cancer gene therapy involves restoration of viral receptor expression

Cancer Gene Therapy - New research in the area of cancer gene therapy detailed

Cancer Gene Therapy - Ovarian cancer metastasis is inhibited by adeno-associated virus-mediated gene transfer

Cancer Gene Therapy - Prostate cancer radiation therapy is aided by the use of gene therapy

Cancer Gene Therapy - Recent findings in cancer gene therapy described

Cancer Gene Therapy - Recent findings in cancer gene therapy provide new insights

Cancer Gene Therapy - Small interfering RNA-mediated depletion of CD44 v5 reduced tumor cell invasion

Cancer Gene Therapy - Tumor angiogenesis is suppressed by oncolytic replication-competent adenovirus

Cancer Research - High leptin receptor mRNA expression and leptin levels in breast cancer predicts poor outcome

Cancer Research - San Diego State University team creates antibody that inhibits tumors growth

Cancer Research - Synovial sarcoma oncoprotein SYT-SSX1 tumorigenesis requires IGF2

Cancer Risk Factors - Respiratory cancer risks among workers with glutaraldehyde exposure analyzed

Cancer Staging - Nomogram can predict side specific extracapsular extension at radical prostatectomy

Cancer Therapy - African American women are bearing unequal burden of colorectal cancer

Cancer Therapy - Breast cancer angiogenesis yields to bevacizumab

Cancer Therapy - Breast cancer chemotherapy gets a boost from antiangiogenic therapy

Cancer Therapy - Cancer angiogenesis and growth is abated by the thioredoxin-1 inhibitor PX-12

Cancer Therapy - Chemotherapy can be enhanced by molecular targeting of BCL2 and BCLXL proteins

Cancer Therapy - Findings advance knowledge in cancer therapy research

Cancer Therapy - Gene expression may predict chemotherapy responses in colorectal cancer patients

Cancer Therapy - Gold nanosphere technology expanded to create safer, more penetrating cancer treatment

Cancer Therapy - High-dose intravenous vitamin C is safe for cancer patients, study says

Cancer Therapy - Introgen's Advexin demonstrates safety and antitumor activity in esophageal cancer

Cancer Therapy - Molecular signatures predict disease progression and prognosis of high grade brain tumors

Cancer Therapy - Parenteral nutrition is not superior to fluid therapy for oral mucositis

Cancer Therapy - Prostate adenocarcinoma treated with radio/brachytherapy show no late Grade 4 or 5 toxicity

Cancer Therapy - Prostate cancer cell superoxide production and apoptosis is enhanced by p53

Cancer Therapy - Recent findings illuminate research in cancer therapy

Cancer Therapy - Recent findings in cancer therapy described

Cancer Therapy - Research in cancer therapy provides new insights

Cancer Therapy - Researchers describe findings in cancer therapy studies

Cancer Therapy - Researchers provide details of new studies and findings in the area of cancer therapy

Cancer Therapy - Solid tumors submit to CD8 T cell attack

Cancer Therapy - Studies add new findings to cancer therapy body of knowledge

Cancer Therapy - Targeted tumor therapy is achieved using an antisense compound

Cancer Therapy - Treatment of solid tumors by epoetin beta therapy unaffected by chemotherapy

Cancer Vaccines - Findings advance knowledge in cancer vaccines research

Cancer Vaccines - Researchers provide details of new studies and findings in the area of cancer vaccines

Cancer Vaccines - Researchers' work adds to cancer vaccines body of knowledge

Carcinogenesis - 1,4-butanediol discounted as a carcinogen

Carcinogenesis - Oral cancer development linked to 8-nitroguanine formation in oral leukoplakia

Carcinogenesis - Proteins with whey-acidic-protein (WAP) motifs implicated in carcinogenesis

Cervical Cancer - Cervical cancer therapy with total laparoscopic radical hysterectomy appears feasible/safe

Cervical Cancer - Recent findings illuminate research in cervical cancer

Cervical Cancer - Smoking may increase risk of squamous cell carcinoma of the cervix

Chemotherapy - Inex licenses three targeted chemotherapy products to Hana Biosciences

Cholangiocarcinoma - Cholangiocarcinoma is treatable with combination virus-radiation therapy

Chronic Myelogenous Leukemia - Chronic myelogenous leukemia linked to enhanced expression and activity of DNA polymerase beta

Clinical Trials - Eli Lilly launches phase 3 trial of targeted oral cancer agent in glioblastoma multiforme

Clinical Trials - Insert Therapeutics receives U.S. FDA approval for IT-101 phase I clinical trial

Clinical Trials - Keryx commences phase 2 multicenter study of perifosine treatment for refractory leukemia

Clinical Trials - Spectrum advances anticancer agent toward registration, plans 2006 phase 3 study start

Colon Cancer - Colon cancer risk may be associated with central adiposity in women

Colon Cancer - Colon cancer targeting of parvoviruses is achieved by insertion in P4 promoter

Colon Cancer - Colon cancer tumor vessels bear significant endoglin expression

Colon Cancer - Physicians warn too few Americans getting screened for colon cancer

Colorectal Cancer - Breast cancer linked to detection of cytokeratin 20-positive cells in blood of patients

Colorectal Cancer - Chemotherapy-induced colorectal cancer cell death inhibited by c-FLIP

Colorectal Cancer - Colorectal cancer angiogenesis is linked to VEGF production

Colorectal Cancer - Colorectal cancer did not show objective response when treated with capecitabine and thalidomide

Colorectal Cancer - Risk of colorectal cancer for individuals with a family history estimated

Colorectal Cancer - Use of DNA pools to identify single nucleotide polymorphisms linked to colorectal cancer validated

Cord Blood Transplantation - Cord blood cell expansion improved following BM-derived mesenchymal stem cell co-culture

DNA Research - Researchers devise way to unravel DNA tangles, offering possibilities for cancer treatment

DNA Research - Smad3 regulates telomerase reverse transcriptase via growth factor beta

Dermatology - Women dermatologists volunteer to teach about sun safety in Miami, Florida

Diagnostics - 1.5 T compared to 3.0 T superparamagnetic iron oxide-enhanced liver MRI

Diagnostics - Clinical applications of mammary ductoscopy discussed

Diagnostics - Findings in diagnostics provide new insights

Diagnostics - Medical Services to deliver Dengue Fever rapid test kits to Middle East

Diagnostics - Researchers report details of new studies and findings in the area of diagnostics

Diet & Nutrition - Standards of nutritional care in pediatric oncology evaluated

Disease Associations - Lung cancer prognosis is worse in HIV/AIDS than in general population

Drug Development - Corroles are specifically delivered to tumor cells via noncovalent conjugates

Drug Development - Simplified ecteinascidin-saframycin analogs synthesized

Drug Development - Stilbenoids of Kobresia nepalensis exhibited DNA topoisomerase II inhibition

Drug Development - Structural basis for antitumor effect of aplyronine A studied

Drug Development - Tumor endothelial cells respond to epidermal growth factor receptor kinase inhibitors

Drug Resistance - MET amplification may uncover cancers sensitive to PHA-665752

Endometrial Cancer - Endometrial cancer risk may be increased in women with weight gain or weight instability

Endometrial Cancer - Endometrial carcinoma chemoresistance involves placental leucine aminopeptidase

Endometrial Cancer - Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis

Environmental Health - Exposure to volcanic mineral associated with increased mesothelioma incidence in Turkey

Esophageal Cancer - Esophageal carcinoma staged preoperatively with multidetector CT and virtual endoscopy

Esophageal Cancer - Patients with mucosal cancer without lymphatic invasion treated with local tumor resection

Esophageal Cancer - Routine compared to selective EUS-guided FNA for staging of esophageal carcinoma

Esophageal Squamous Cell Carcinoma - Esophageal squamous cell carcinoma predicted MTR A2756G polymorphism

Esophageal Tumors - Hypoxic esophageal tumors responded to radiotherapy with addition of irinotecan

Facilities - MUSC Hollings Cancer Center announces affiliation with Carolina Regional Cancer Center

Finance - Dendreon reports fourth quarter and year-end results, revenue drops

Finance - EDAP TMS S.A. reports strong growth in fourth-quarter and year-end results

Finance - EpiCept releases first financial report since merger with Maxim Pharmaceuticals

Finance - Keryx reports 2005 increase in cash, other assets spurred by common stock offering

Finance - Peregrine Pharmaceuticals reports net loss of $3.1 million in third quarter

Finance - Point Therapeutics reports a net loss of $5,899,000 for fourth quarter

Finance - Pro-Pharmaceuticals reports fourth quarter net loss of $1,749,000

Finance - Progenics Pharmaceuticals reports fourth quarter revenues were $2 million

Finance - Spectrum reports 2005 net loss of $18.6 million, compared to $12.3 million in 2004

Finance - Valera reports 2005 net revenues of $26.8 million driven by prostate cancer treatment

Finance - XOMA reports total 2005 revenues of $18.7 million, up from $3.7 million in 2004

Fitness & Wellness - Exercise raises VEGF receptor levels in study volunteers

Gastric Cancer - Clinicopathological properties of poorly differentiated adenocarcinoma of the stomach described

Gastric Cancer - Disseminated peritoneal scirrhous gastric cancer is responsive to gene-drug therapy

Gastric Cancer - Gastric cancer progression is driven by protease-activated receptor-2

Gastric Cancer - Reports advance knowledge in gastric cancer research

Gastrointestinal Cancer - Analysis of cancer prevention strategies for gastrointestinal cancer conducted

Gene Research - Cancer pathogenesis involves small noncoding microRNA

Gene Research - Drug that switches on genes improves myelodysplastic syndrome treatment

Gene Transfer - LYVE-1 cDNA delivery creates blocking antibodies

Genetic Research - Compendia Bioscience obtains exclusive rights to commercialize Oncomine

Genetic Research - Roles of FHIT and WWOX fragile genes in cancer discussed

Genetics & Genomics - GenOway contracts with Italy-based oncology institutes for gene-modified mouse models

Germ Cell Cancer - Surveillance programs for stage I nonseminomatous germ cell tumors described

Glioblastomas - Intravenous compared to intraarterial ACNU administration in newly diagnosed glioblastomas

Gliomas - Glioma cell invasion enhanced by EFA6A

Graft-versus-Host Disease - Interleukin-18 levels are a useful indicator of acute graft-versus-host disease

Graft-versus-Host Disease - Women with breast or hematologic malignancy more likely to develop GI GVHD after ASCT

Head & Neck Cancer - Cancer lymphangiogenesis may stem from inducible nitric oxide synthase activity

Head & Neck Cancer - Head and neck squamous cell carcinoma treated by carboplatin and radiotherapy

Head & Neck Cancer - Head and neck squamous cell carcinoma treated by docetaxel, cisplatin, and 5-fluorouracil

Head & Neck Cancer - Recent findings in head & neck cancer described

Head & Neck Cancer - Squamous cell head and neck cancer prognosticated by anemia

Healthcare Coverage - Del. Brown's bill to ensure access to cervical cancer screening passes West Virginia legislature

Healthcare Coverage - UnumProvident reports cancer was top reason for long-term absence from work in 2005

Hematopoiesis - Fetal hematopoiesis altered by genetic reduction of class IA PI-3 kinase activity

Hematopoiesis - Megakaryocytopoiesis is stimulated by arsenic trioxide through upregulation of GATA-2 expression

Hepatitis B Virus - HBV X antigen downregulates E-cadherin in hepatocellular carcinoma

Hepatitis C Virus - HCV-positive patients differ in presentation of diffuse large B-cell lymphoma

Hepatocellular Cancer - Studies describe new findings in hepatocellular cancer research

Hepatocellular Carcinoma - Factors identified that are linked to early recurrence of hepatocellular carcinoma after resection

Hepatocellular Carcinoma - HCC changes occur after sustained interferon response to hepatitis C virus

Hepatocellular Carcinoma - HCC is influenced by alcohol consumption and ADH2 and ALDH2 gene polymorphisms

Hepatocellular Carcinoma - HCC proteomic profiling reveals heat-shock protein up-regulation

Hepatocellular Carcinoma - HCC tumorigenicity is reduced by knock-down of hepatitis B virus X protein

Hepatocellular Carcinoma - Hepatocellular carcinoma treated by menatetrenone, a vitamin K2 analog

Hepatocellular Carcinoma - Hepatocellular carcinoma treated by radiofrequency thermal ablation

Hepatocellular Carcinoma - Hepatocellular carcinoma treated by transcatheter arterial chemoembolization

Hepatocellular Carcinoma - Liver cancer angiogenesis could be restricted by Sprouty 2 regulation

Hepatocellular Carcinoma - Liver cancer growth, but not angiogenesis, responds to combination therapy

Hepatocellular Carcinoma - Primary HCC serum associated fucosylated glycoproteins may be diagnostic

Hodgkin Lymphoma - Diagnosis of secondary malignancies after primary treatment of Hodgkin lymphoma could be difficult

Human Herpesvirus - Human herpes virus type 8 seroprevalence rate is intermediate-high and stable in Northern Sweden

Human Papillomavirus - Human papillomavirus-associated oropharyngeal cancers with favorable prognosis identified

Human Papillomavirus - Human papillomaviruses are genotyped by bead-based multiplex method

Human Papillomavirus - Study group urges establishment of international standard for HPV 16 antibodies

Human Papillomavirus Vaccine - Dendritic cell activation by HPV-16 vaccine involves a specific C-type lectin

Imaging - MediSpectra receives U.S. FDA approval for the Luma Cervical Imaging System

Imaging - Positron emission tomography targets oncolytic virus in prostate cancer therapy

Imaging - Researchers' work adds to imaging body of knowledge

Immunotherapy - Heat labile Escherichia coli enterotoxin is potential adjuvant for transcutaneous cancer immunotherapy

Immunotherapy - Study to determine how to protect patients with weakened immune systems from influenza

Leukemia - ATM gene promoter analysis of childhood lymphoid malignancies conducted

Leukemia - Acute myeloid leukemia linked to cyclin A1 expression

Leukemia - Adult T cell leukemia treated by curcumin

Leukemia - Frequency of chronic lymphocytic leukemia expressing VH 1-69 was low in Japanese

Leukemia - Myeloid leukemia cell differentiation involves a novel signaling molecule

Leukemia - New findings in the area of leukemia described

Leukemia - New findings in the area of leukemia detailed

Leukemia - New research in the area of leukemia detailed

Leukemia - Patients with acute myelogenous leukemia should receive consolidation before autotransplantation

Leukemia - Pre-B lymphoblastic leukemia cell aberrant splicing is induced by BCR-ABL1

Leukemia - Researchers publish new studies and findings in the area of leukemia

Leukemia - Smaller white-matter volumes linked to neurocognitive performance deficits among leukemia survivors

Leukemia - Studies add new findings to leukemia body of knowledge

Liposome Delivery - Liposome-DNA complexes inhibit tumor angiogenesis and elicit antitumor activity

Liver Cancer - Florida medical practice treats metastatic cancer using Varian image-guided radiotherapy technology

Liver Cancer - Liver cancer over-expresses angiogenesis growth factor

Liver Cancer - Liver cancer patients are often treatable

Lung Cancer - Dana Reeve's death highlights women's lung cancer risks

Lung Cancer - Histopathology of lung cancer in relation to radon exposure and silicosis analyzed

Lung Cancer - Lung cancer cannot be staged adequately by PET/CT of the chest during shallow breathing

Lung Cancer - Lung cancer treated by carboplatin/gemcitabine, an alternative therapy regimen

Lung Cancer - Lung cancer treated by irinotecan and cisplatin

Lung Cancer - Nonsmall cell lung cancer associated with cell-free circulating hTERT mRNA

Lung Cancer - Pharmacokinetics of amrubicin in lung cancer patients characterized

Lung Cancer - Reports describe recent advances in lung cancer research

Lung Cancer - Researchers describe findings in lung cancer studies

Lung Cancer - Resected non-small cell lung cancer linked to extreme chemotherapy resistance

Lung Cancer - Secular changes in sex-specific lung cancer incidence rates in urban Chinese population examined

Lung Cancer - Stage Ib lung cancer treated by sublobar resection with brachytherapy

Lung Cancer - Video-assisted thoracic surgery lobectomy for lung cancer evaluated

Lymphoma - Lymphoma growth is sustained by fibroblast growth factor

Lymphoma - Lymphoma survival predicted by integrated clinical and gene expression data

Lymphoma - Studies describe new findings in lymphoma research

Marketing - Helsinn and Pfizer sign a license agreement for the marketing of Aloxi in South Africa

Marketing - IDM and Medison Pharma sign an exclusive marketing agreement for Junovan in Israel

Marketing - Neoprobe renews marketing agreement with Ethicon Endo-Surgery

Melanoma - Dermatomyositis occurring in patients with malignant melanoma stage IV linked to poor prognosis

Melanoma - Impact of lymphoscintigraphy technique on outcome of sentinel node biopsy in melanoma discussed

Melanoma - Melanoma is regressed in a murine model by RLIP76 depletion

Melanoma - Melanosomal targeting sequences target epitope presentation and mobilization

Melanoma - Researchers detail new studies and findings in the area of melanoma

Melanoma - Researchers publish new studies and findings in the area of melanoma

Melanoma - Ultraviolet B sensitivity of lymphocytes identified as risk factor for melanoma

Melanoma Vaccines - New data illuminates research in melanoma vaccines

Melanoma Vaccines - Recent studies add new data to melanoma vaccines research

Melanoma Vaccines - Reports add new data to melanoma vaccines research

Meningiomas - Primary and recurrent meningiomas require new treatment strategies

Metastasis - Colorectal cancer liver metastasis may recur due to angiogenesis factors after resection

Multiple Myeloma - Early multiple myeloma treatment failure is initiated by synergy between cyclin D2 and CKS1B

Multiple Myeloma - Multiple myeloma peripheral blood progenitor cells are mobilized and harvested by pegfilgrastim

Multiple Myeloma - Multiple myeloma responds to thalidomide monotherapy

Myelodysplastic Syndrome - Study recommends treatment change for pre-leukemia disease

Myeloma - Multiple myeloma is rarely associated with PTEN deletions and mutations

Myeloma - Multiple myeloma overexpressed genes identified in chromosome regions

Myeloma - Outcome of myeloma not improved with addition of valspodar

Natural Products - 5,6:8,9-Diepoxy and other cytotoxic sterols isolated from marine sponge

Nephroblastoma - Wilms tumor complicated by liver metastases linked to less favorable outcome

Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma treated with less intensive therapy

Oncology - Findings describe new data in oncology research

Oncology - New findings in the area of oncology detailed

Oncology - Tumor angiogenesis and monocyte trafficking are driven by integrin interaction

Oncology - Urothelial cancer displays matrix metalloproteinase localization

Ovarian Cancer - Data advance knowledge in ovarian cancer research

Ovarian Cancer - Effective ovarian cancer treatment strategies target Raf-1 mRNA

Ovarian Cancer - Mdr-1 polymorphism G2677T/A correlates with paclitaxel response in ovarian cancer

Ovarian Cancer - Ovarian cancer progression is predicted preoperatively by angiogenesis protein

Palliation - Improved chemotherapy drugs improve quality of life for bone marrow cancer patients

Pancreatic Cancer - Pancreatic cancer cells react to structurally optimized celecoxib derivative

Pancreatic Cancer - Pancreatic head carcinoma in elderly patients can be treated by surgery but with risks

Patents - EntreMed's patent covers broad range of indications for 2-methoxyestradiol

Periampullary Tumors - Periampullary tumors with CT grades A to D staged with laparoscopic ultrasound

Personnel - Dendreon names Mark Frohlich vice president of clinical affairs

Personnel - Dr. Judith Hemberger joins ZymoGenetics board of directors

Personnel - Frances W. Preston joins Bionovo's board of directors

Personnel - Joel Lajeunesse named VP, division head of pharmacy, at M.D. Anderson Cancer Center

Personnel - MedImmune broadens management team with five additional leaders in key strategic areas

Personnel - National Cancer Coalition creates international advisory council

Personnel - Seattle Genetics appoints Dr. Daniel Hoth to board of directors

Personnel - Tracon Pharmaceuticals names key management team members to help develop cancer therapy pipeline

Pharmaceutical Research - Engineering Fc region of antibodies raises toxicity to cancer cells, Xencor research shows

Pharmaceutical Research - Thalidomide shows no interaction with P-glycoprotein

Philanthropy - Holland America Line sponsors "On Deck for the Cure" to raise money to fight breast cancer

Physiology - Novel targets identified in a phosphatidylinositol 3-kinase-independent pathway

Pott Puffy Tumors - Pott puffy tumor described as rare complication of mastoiditis

Preventive Medicine - Sun safety curriculum improved middle school students' knowledge of sun protection

Prognostics - Clinical factors used to select patients who would benefit from hepatic metastasectomy

Prostate Cancer - Bone implants in SCID mice evaluated as a model of prostate cancer bone metastasis

Prostate Cancer - Cell Genesys to present data from two GVAX cancer immunotherapy clinical trials

Prostate Cancer - Detection of bone metastases from high-risk prostate cancer improved by SPECT

Prostate Cancer - Hormone-sensitive prostate cancer treated with zoledronic acid therapy

Prostate Cancer - Human prostate cancer is associated with G-protein coupled receptor overexpression

Prostate Cancer - Impact of prostate cancer diagnosis on patients' mental health evaluated

Prostate Cancer - Pathological characteristics of prostate cancer discussed

Prostate Cancer - Prostate cancer diagnosed after repeat biopsies linked to favorable prognosis

Prostate Cancer - Prostate cancer epithelial cell channels display differential roles

Prostate Cancer - Prostate cancer malignancy linked to Aurora B expression

Prostate Cancer - Prostate cancer predicted by prostate specific antigen in black American men

Prostate Cancer - Prostate cancer screening in high-risk African American men discussed

Prostate Cancer - Prostate cancers are effectively treated using oncolytic herpes simplex virus

Prostate Cancer - Regressive changes after antihormonal therapy in prostatic carcinoma analyzed

Prostate Cancer - Reports advance knowledge in prostate cancer research

Prostate Cancer - Research add new data to prostate cancer body of knowledge

Prostate Cancer - Researchers describe findings in prostate cancer studies

Prostate Cancer - Researchers provide details of new studies and findings in the area of prostate cancer

Prostate Cancer - Researchers' work adds to prostate cancer body of knowledge

Proteomics - Caprion Pharmaceuticals announces acquisition of novel therapeutic peptide applicable in oncology

Proteomics - Deformability, dynamics, and remodeling of cytoskeleton of adherent living cells are considered

Proteomics - Endogenous factors influence angiogenin production

Proteomics - The angiogenesis inhibitor histidine-rich glycoprotein disrupts endothelial cell movement

Radiotherapy - Link between quality of life and fatigue in cancer patients receiving radiotherapy assessed

Radiotherapy - Non-small cell lung cancer treated by stereotactic hypofractionated radiotherapy

Radiotherapy - Sulfoquinovosylmonoacylglycerol sensitizes tumor vessels to radiation therapy

Rectal Cancer - Technique of total mesorectal excision in rectal cancer surgery described

Renal Angiomyolipomata - Renal angiomyolipomata in patients with tuberous sclerosis complex treated by embolization

Renal Cell Carcinoma - Renal cell carcinoma prognosticated by platelet count

Renal Rhabdomyosarcoma - Case of puerperal renal rhabdomyosarcoma described

Renal Tumors - Renal tumors treated by radiofrequency ablation

Rhabdomyosarcomas - Rhabdomyosarcoma should be treated by complete tumor resection prior to chemotherapy

Sacrococcygeal Teratoma - Factors relating to sacrococcygeal teratoma recurrence in children examined

Sexual & Reproductive Health - Study shows lifestyle and health related to satisfying sex life as men age

Skin Cancer - Researchers link human papillomavirus to common skin cancer

Soft Tissue Sarcomas - Soft tissue sarcoma should not be treated with gemcitabine as first-line chemotherapy

Solitary Fibrous Tumors - Case of solitary fibrous tumor of the larynx reported

Squamous Cell Carcinoma - Incidence of squamous cell carcinoma in Zimbabwean population described

Squamous Cell Carcinoma - Oral squamous cell carcinoma linked to WWOX gene alterations

Squamous Cell Carcinoma - Poor prognosis in oral squamous cell carcinoma linked to reduced E-cadherin expression

Squamous Cell Carcinoma - Squamous cell carcinoma of the esophagus staged by preoperative laparoscopy

Squamous Cell Carcinoma - Squamous cell carcinoma of the head and neck linked to p16 gene alterations

Stem Cell Research - Activated NK cells are capable of killing mesenchymal stem cells

Stem Cell Research - Allogeneic hematopoietic stem cell transplantation is a potent immunotherapy

Stem Cell Research - Research into the behavior of leukemic cells may enhance recovery from radiation and chemo

Stem Cell Research - Stem cell-derived dendritic cells induce immunity against metastatic melanoma

Stem Cell Transplantation - ASCT is feasible in selected elderly patients with non-Hodgkin lymphoma

Stem Cell Transplantation - Natural killer-cell lineage neoplasms treated by hematopoietic SCT therapy

Stem Cell Transplantation - Post-hematopoietic stem cell transplant G-CSF does not affect risk of GVHD or survival

Stem Cell Transplantation - Stem cell transplant survival in CML associated with higher 30-day lymphocyte count

Stem Cell Transplantation - Transplant-related mortality increased in non-Caucasians undergoing standard sibling SCT

Surgical Technology - Bladder cancer treated by virtual cystoscopy via instillation of dilute contrast medium

Surgical Technology - Subtotal esophagectomy for esophageal cancer performed using supercharge technique

Testicular Seminoma - Treatment of testicular seminoma by adjuvant chemotherapy evaluated

Thyroid Cancer - Metastatic thyroid carcinoma restaged in real-time by FDG-PET scanning

Tongue Cancer - Poor prognosis of tongue carcinoma associated with expression of Bcl-2

Transforming Growth Factor - Transforming growth factor-beta signaling pathways are altered in human cancer

Transitional Cell Carcinoma - Transitional cell carcinoma treated by gemcitabine and paclitaxel second-line chemotherapy

Transplantation Biology - Liver transplantation can be advantageous for hepatitis C virus-positive patients

Transplantation Biology - Liver transplantation can increase survival in children with hepatocellular carcinoma

Tumor Lysis Syndrome - Hyperuricemia corrected with reduced-dose rasburicase

Wilms Tumor - Value of surgery in directing therapy for patients with Wilms tumor assessed

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