Stem Cell Transplantation

Long-term donor health associated with recipient stem cell transplantation outcome

Published in Cancer Weekly, April 17th, 2006

Long-term donor health is associated with recipient HSCT outcome.

According to a recent report from the People's Republic of China, "Data on long-term follow-up of donors for hematopoietic stem cell transplantation (HSCT) are limited. Donors of 612 adult allogeneic HSCT were studied, at a median of 81 (14-181) months post-HSC donation."

"Nine donors had severe health problems. Five donors died from aggressive malignancies or terminal illness, at a median of 41 (16-57) months postdonation.

"Notably, all their recipients had leukemic relapses. In contrast, donors of recipients in remission were all living," wrote W.Y. Au and...

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Source: Cancer Weekly (2006-04-17)

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