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Cancer Vaccines

New findings in cancer vaccines described

Published in Cancer Weekly, April 24th, 2006

Data on cancer vaccines are outlined in reports from Italy, the United States and the United Kingdom.

Study 1: Anaplastic lymphoma kinase is a lymphoma antigen suitable for immune interventions.

According to a study from Italy, "Anaplastic lymphoma kinase (ALK) oncogenic fusion proteins, expressed in about 60% of anaplastic large cell lymphomas (ALCL), are tumor-specific molecular targets for such a malignancy. One of the promising ALK-targeted therapeutic options is cancer vaccination. In this study, we investigate whether ALK is a tumor-associated antigen suitable for immune interventions. The frequency and the functional phenotype of the anti-ALK...

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