Published in Cancer Weekly, April 24th, 2006
Study 1: Tumor cell adhesion and packing density might contribute to drug resistance.
According to scientists in Canada, "To reach cancer cells in optimal quantities, therapeutic agents must be delivered to tumors through their imperfect blood vascular system, cross vessel walls into the interstitium, and penetrate multiple layers of tissue. Strategies to enhance drug penetration have potential to improve therapeutic outcome."
"The development of multicellular layers (MCLs), in which tumor cells are grown on a semipermeable Teflon support...
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