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Breast Cancer

Study finds two genes predict outcome for breast cancer patients

Published in Cancer Weekly, April 24th, 2006

Mayo Clinic researchers report that the expression of two novel genes within the tumors of women with early stage breast cancer may allow identification of women who are and are not at risk for early relapse or cancer-related death. Results of the study are published in a recent issue of Clinical Cancer Research.

"The HOXB13 and IL17BR gene profile was previously discovered as a potential marker of relapse in hormone-receptor positive breast cancer treated with tamoxifen," says Matthew Goetz, MD, who co-led the project with James Ingle, MD and Fergus Couch, PhD "Our new study shows that the marker is only useful for identifying women with a higher risk in the...

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