Melanoma

Melanoma treated by biochemotherapy regimen with temozolomide

Published in Cancer Weekly, May 1st, 2006

Metastatic melanoma could be treated by a biochemotherapy regimen plus temozolomide (Temodal).

"Our objective was to evaluate the toxicity and antitumor efficacy of concurrent biochemotherapy in metastatic melanoma patients and the effectiveness of adding temozolomide to protect the brain from metastases. Twenty-three patients with advanced inoperable melanoma were hospitalized for 5-6 days for the following treatment: cisplatin 20 mg/m² daily for 4 days, vinblastine 1.6 mg/m² daily for 4 days and oral temozolomide 250 mg/m² daily for 5 days, with 18 x 10⁶ IU/m² intravenous interleukin-2 by continuous infusion for 4...

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Source: Cancer Weekly (2006-05-01)

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