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Colorectal Cancer

Colorectal cancer prognosticated by sentinel lymph node mapping

Published in Cancer Weekly, May 15th, 2006

Colorectal cancer (CRCa) could be prognosticated by sentinel lymph node (SLN) mapping (M).

"SLNM for staging in CRCa remains controversial and needs to be validated. This study analyzes results of SLNM at a multi-institutional level for CRCa. Group A patients underwent SLNM with 1 to 3 mL of 1% lymphazurin," researchers in the United States reported.

"First 1 to 4 blue lymph nodes were designated as SLNs and had focused analysis. Group B had standard resection and nodal staging. Patients with a minimum of 2 years of follow-up were analyzed for recurrence. Overall nodal metastasis were 50% for 500 group A patients versus 35% for 368 group B patients....

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