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Rectal Cancer

Patients with early rectal cancer may benefit from postoperative chemoradiotherapy

Published in Cancer Weekly, May 15th, 2006

Patients with early rectal cancer patients benefit from postoperative chemoradiation therapy or a more radical surgical procedure than local excision.

"Local excision has been accepted therapy for T1 rectal cancers. A recent study demonstrated that primary tumors with deeper submucosal invasion were associated with a higher rate of lymph node metastases than those with shallow invasion," investigators in the United States reported.

"Our aim was to determine the effect of the depth of submucosal penetration on recurrence and mortality rates following transrectal excision of T1 tumors," explained K. Wirsing and colleagues, Spectrum Health-Blodgett...

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