DNA Research
Human cells protected from oxidative DNA damage by FPG protein
Published in Cancer Weekly, May 22nd, 2006
According to a study from Italy, "Repair of some oxidized purines such as 8-oxo-7,8-dihydroguanine (8-oxoG) is inefficient in human cells in comparison to repair of other major endogenous lesions (e.g. uracil, abasic sites or oxidized pyrimidines). This is due to the poor catalytic properties of hOGG1, the major DNA glycosylase involved in 8-oxoG removal."
"The FPG protein from E. coli is endowed with a potent 8-oxoG glycolytic activity coupled with a beta,delta-AP lyase," explained M. Ropolo and colleagues, National Institute for...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2006-05-22)
More Articles from Cancer Weekly
- Brain Cancer
Brain cancer tumorigenesis inhibited by schwannomin - Leukemia
Leukemia was treated by cytarabine in combination with 7-hydroxystaurosporine - Lung Cancer
Lung cancer incidence preceded by promoter hypermethylation of multiple genes - Prostate Cancer
Prostatic metastatic migration potentiated by arachidonic acid - Adenocarcinoma
Lung adenocarcinoma cells may be targeted by short hairpin RNA targeting EGFR - Adverse Drug Reaction
Strategies to reduce the risk of chemoprevention discussed - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
