Lung Cancer
Lung cancer incidence preceded by promoter hypermethylation of multiple genes
Published in Cancer Weekly, May 22nd, 2006
"A sensitive screening approach for lung cancer could markedly reduce the high mortality rate for this disease. Previous studies have shown that methylation of gene promoters is present in exfoliated cells within sputum prior to lung cancer diagnosis," scientists writing in the journal Cancer Research reported.
"The purpose of the current study is to conduct a nested case-control study of incident lung cancer cases from an extremely high-risk cohort for evaluating promoter methylation of 14 genes in sputum," explained S.A. Belinsky and colleagues, Lovelace...
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Source: Cancer Weekly (2006-05-22)
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