Drug Development
Fusion protein under development for radioimmunotherapy of hematologic malignancies
Published in Cancer Weekly, May 29th, 2006
According to recent research from the United States, "Acute myelogenous leukemia (AML) currently kills the majority of afflicted patients despite combination chemotherapy and hematopoietic cell transplantation (HCT). Our group has documented the promise of radiolabeled anti-CD45 monoclonal antibodies (Ab) administered in the setting of allogeneic HCT, for AML, but toxicity remains high, and cure rates are only 25% to 30% for relapsed AML."
"We now show the superiority of pretrargeted radioimmunotherapy...
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Source: Cancer Weekly (2006-05-29)
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