Published in Cancer Weekly, May 29th, 2006
"SEREX has been applied to esophageal SCC, and the TRIM21 gene was identified as a novel SEREX antigen of esophageal SCC," wrote M. Kuboshima and colleagues, Chiba University.
They explained, "The presence of s-TRIM21-Abs was confirmed by Western blotting using bacterially expressed TRIM21 gene product and was evaluated for clinicopathological significance in patients with esophageal SCC. s-TRIM21-Abs were detected in 18 (20%) of 91 patients with esophageal SCC but not in 42 healthy donors."
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Source: Cancer Weekly (2006-05-29)
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