Published in Cancer Weekly, May 29th, 2006
"We have previously shown that adenoviral-mediated melanoma differentiation-associated gene-7 (Ad.mda-7) therapy induces apoptosis in ovarian cancer cells. However, the apoptosis induction was low and directly correlated with infectivity of Ad.mda-7," wrote P.J. Mahasreshti and colleagues, University of Alabama. "The objective of this study was to derive ovarian cancer targeted infectivity-enhanced adenoviral...
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