Ovarian Cancer
Epithelial ovarian cancer survival lowered with stromal matrix metalloproteinase overexpression
Published in Cancer Weekly, May 29th, 2006
"MMP are proteolytic enzymes implicated in cancer progression and metastasis. We sought to determine the role of epithelial (tumor cell-derived) and stromal (host-derived) expression of MMPs in predicting the clinical outcome of patients with EOC," scientists in the United States reported.
"MMP-2, MMP-9, and membrane type 1 (MT1)-MMP expression was evaluated using immunohistochemistry in 90 invasive EOCs, and samples were scored for epithelial and stromal staining," explained A.A. Kamat and colleagues, M.D. Anderson Cancer...
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Source: Cancer Weekly (2006-05-29)
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