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Genetics & Genomics

Human cancers classified molecularly in real-time

Published in Cancer Weekly, June 5th, 2006

A study from the United States has reported on the molecular classification of human cancers using a 92-gene real-time quantitative polymerase chain reaction (RT-PCR) assay.

"Correct diagnosis of the tissue origin of a metastatic cancer is the first step in disease management, but it is frequently difficult using standard pathologic methods. Microarray-based gene expression profiling has shown great promise as a new tool to address this challenge. Adoption of microarray technologies in the clinic remains limited," wrote X.J. Ma and colleagues, Arcturus BioScience Inc.

"We aimed to bridge this technological gap by developing a RT-PCR assay. We...

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