Published in Cancer Weekly, June 5th, 2006
"The purpose of this study was to determine the response to CPT-11 administered every 3 weeks to adults with progressive malignant glioma, treated with or without enzyme-inducing antiepileptic drug (EIAED) therapy, at the recommended phase 2 dose determined from a previous phase 1 study. Adult patients age 18 or older with a KPS of 60 or higher who had measurable recurrent grade III anaplastic glioma (AG) or grade IV glioblastoma multiforme (GBM) were eligible," researchers in the United States reported.
"No more than one prior chemotherapy was allowed, either...
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