Allergy & Immunology

Rheumatoid arthritis drug linked to serious infections and cancers

Published in Cancer Weekly, June 5th, 2006

A new meta-analysis of many previous studies of TNF- (tumor necrosis factor) blocking antibodies for treatment of rheumatoid arthritis has confirmed a previously discovered increased risk for serious infection and has found that cancer also is a potential risk associated with the drugs.

"This study shows a strong association between treatment with TNF-blocking antibodies and the development of serious infections, such as pneumonia, and cancers," said Eric Matteson, MD, Mayo Clinic rheumatologist and a senior study investigator. "It's a very serious issue. TNF-blocking antibodies are effective for treatment for rheumatoid arthritis and related conditions, but patients...

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Source: Cancer Weekly (2006-06-05)

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