Cancer Therapy

Gadolinium neutron capture therapy may benefit from a novel gadolinium delivery system

Published in Cancer Weekly, June 5th, 2006

Gadolinium(Gd)-encapsulated liposomes may be useful for delivering Gd into solid tumors for neutron capture therapy (NCT) and tumor imaging.

According to recent research from the United States, "Gd-NCT is a promising cancer therapy modality. One of the key factors for a successful Gd-NCT is to deliver and maintain a sufficient amount of Gd in tumor tissues during neutron irradiation."

U.A. Le and colleagues, Oregon State University, explained, "We proposed to prepare a Gd delivery system by complexing a Gd-containing compound, diethylenetriaminepentaacetic acid (Gd-DTPA), with a polycationic peptide, poly-L-lysine (pLL), and then encapsulate the...

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Source: Cancer Weekly (2006-06-05)

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