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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . June 12th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Apoptosis - Melanoma apoptosis triggered by novel Bcl-x splice product, Bcl-x(AK)

Breast Cancer - Breast cancer risk increased in developing countries due to circadian disruption

Hurthle Cell Cancer - Encapsulated Hurthle cell carcinoma recurrence predicted by presence of 4 foci of vascular invasion

Neuroblastoma - Poor neuroblastoma outcome could be due to high-level MRP1 expression

Acoustic Neuroma - Acoustic neuroma patients' quality of life used in timing of surgery

Adenocarcinoma - Adenocarcinoma of esophagus and gastroesophageal junction linked to alteration of 1q and 8p genes

Adenoviral Gene Therapy - Adenovirus-mediated gene expression is improved by a polyethylene glycol vehicle

Adenoviral Gene Therapy - Renal cell carcinoma growth suppressed by vascular endothelial growth factor receptor

Adverse Drug Reaction - Cytosolic 5'-nucleotidase I systemic chemotherapy is toxic

Adverse Drug Reaction - Retroviral vector suicide strategy exhibits improved safety in cancer therapy

Anaplastic Oligodendroglioma - High-dose thiotepa with stem cell rescue effective long-term in anaplastic oligodendroglioma

Apoptosis - Apoptin-induced cell death is dependent on Bcl-2 family members and Apaf-1

Awards - Spa Finder presents Visionary Award to Stephen and Lyn Krant for melanoma awareness efforts

Basal Cell Carcinoma - Modified fast-track protocol for periocular basal cell carcinomas deemed feasible

Benign Prostatic Hyperplasia - Nymox reports positive efficacy data for benign prostatic hyperplasia drug, NX-1207

Bladder Cancer Diagnostics - Clinical benefits of UroVysion DNA test highlighted by bladder cancer experts in urology

Brain Cancer - Blood volume of brain tumors correlated with blood-oxygenation-level-dependent signal in motor cortex

Brain Cancer - Brain tumors express low levels of the antiangiogenic protease ADAMTS-8

Brain Cancer - Cervical spinal cord stimulation increases glucose metabolism in brain tumors

Breast Cancer - Body mass index and hormone therapy interactions correlate with specific breast cancers

Breast Cancer - Breast cancer frontal/sagittal/horizontal plane location influenced axillary lymph node involvement

Breast Cancer - Breast cancer long-term survival predicted by mitotic activity index

Breast Cancer - Breast cancer lymph system angiogenesis is driven by COX-2 expression

Breast Cancer - Breast cancer prognosis is better where diffuse inflammation is present

Breast Cancer - Breast cancer recurrence rate lowered by biweekly doxorubicin/cyclophosphamide plus paclitaxel

Breast Cancer - Breast cancer risk associated with adiposity may be related to endogenous sex steroids

Breast Cancer - Breast cancer risk due to circadian rhythm disruption warrants further study

Breast Cancer - Dartmouth researchers test new technique to examine breast tissue

Breast Cancer - Fibroadenoma growth is regulated by a hormone-receptor mechanism

Breast Cancer - Higher breast density may be associated with even low alcohol consumption

Breast Cancer - Link between breast cancer risk and prolactin requires further study

Breast Cancer - Most breast cancers coexpress leptin, although OBR-S is an independent prognostic factor

Breast Cancer - Patients with breast cancer lesions smaller than 10 mm should avoid unnecessary surgery

Breast Cancer - Raloxifene-resistant breast cancers may be derivatives of HER2/neu overexpression

Breast Cancer - US and FNAC of axilla in follow-up of sentinel node negative breast cancer patients not needed

Breast Cancer - Use of breast MRI can be cost-effective for some women at high risk of breast cancer

Breast Cancer - Weight gain in women increases risk of all types of breast cancer

Breast Cancer Screening - Core biopsy is recommended for all papillary lesions to enhance malignancy prediction

Breast Cancer Screening - Racial disparities in breast cancer outcomes may be due to lower mammography rates

Business & Finance - DOR BioPharma, Inc. reports first quarter financials, reviews achievements

Business & Finance - EntreMed reports first quarter 2006 financial results

Business & Finance - IDM Pharma reports first-quarter revenue of $2.3 million

Business Update - CytoCore announces new auditors, retracts portion of previous announcement

Business Update - Digi-Solve unveils outsourced digitizing service to ease transition to digital mammography

Business Update - Insightful awarded research contracts worth over $1.3M by U.S. National Cancer Institute

Business Update - Laureate Pharma, Iconic Therapeutics announce immunoprotein manufacturing agreement

Business Update - Two Swedish cancer centers to purchase radiotherapy equipment from Varian Medical Systems

Cancer Diagnosis - Depressive episode after cancer diagnosis linked to amygdala volume

Cancer Diagnosis - Neoprobe receives U.S. FDA clearance for Lymphoseek clinical study

Cancer Gene Therapy - Endostatin gene therapy and radiation significantly affect cells and cytokines

Cancer Gene Therapy - Epithelial ovarian cancer growth arrested by antisense suppression of Pygopus2

Cancer Gene Therapy - Gene transfer enhances antitumor activity of hematopoietic stem cell transplantation

Cancer Gene Therapy - Human glioma cell growth is inhibited by antisense human telomerase RNA

Cancer Gene Therapy - Pancreatic ductal adenocarcinoma responds to oligonucleotide-based combination therapy

Cancer Gene Therapy - Prostate-specific membrane antigen tumor targeting is efficiently achieved

Cancer Gene Therapy - Ribonucleotide reductase M2 mRNA levels determined after antisense drug treatment

Cancer Immunotherapy - Preexisting tumors can be treated by fractalkine/CX3CLI-expressing dendritic cells

Cancer Incidence - Increased cancer incidence and mortality in men linked to low vitamin D intake

Cancer Research - Data monitoring board recommends interim analysis of survival data for Satraplatin phase III trial

Cancer Risk Factors - Cancer risk not significantly related to milk and dairy product consumption

Cancer Risk Factors - Cancer risks among BRCA1 and BRCA2 mutation carriers affected by genetic and nongenetic factors

Cancer Risk Factors - Lower cancer rates among Parkinson disease patients may be due to high melatonin levels

Cancer Screening - Cancer screening rates may be improved by telephone support intervention

Cancer Surgery - Cancer surgery risks and opportunities discussed

Cancer Therapy - Angiogenic factors correlate with bone markers following zoledronic acid infusion

Cancer Therapy - Cancer angiogenesis is hampered by synergy between MSC and irinotecan

Cancer Therapy - Cervical cancer malignant phenotype is reversed by delivery of antisense RNA

Cancer Therapy - Chemotherapy-induced nausea in women may be prevented by addition of aprepitant

Cancer Therapy - Chewing gum containing cysteine can prevent upper digestive tract cancers

Cancer Therapy - Colon and pancreatic cancers show a heightened response to therapy combining cetuximab and DC101

Cancer Therapy - E2F1 is a critical modulator of cellular senescence in cancer

Cancer Therapy - Glioma treatment utilizes novel transcriptional targeting strategy

Cancer Therapy - Gold 'thermal scalpel' targets cancer

Cancer Therapy - Liver metastatic disease can be treated with laparoscopic hepatic artery catheterization

Cancer Therapy - Mayo Clinic offers suggestions to deal with emotional challenges cancer survivors face after successful treatment

Cancer Therapy - Nereus Pharmaceuticals initiates phase I clinical trial for anticancer proteasome inhibitor

Cancer Therapy - No difference in voice quality after comparing different treatments for vocal cord cancer

Cancer Therapy - PTC Therapeutics initiates phase Ia clinical trial of PTC299 for solid cancers

Cancer Therapy - Researchers make vitamin E offshoot a potent cancer killer

Cancer Therapy - Researchers uncover new mechanism of tumor suppressor

Cancer Therapy - Squamocin inhibits proliferation of leukemia cells via G2/M arrest

Cancer Therapy - Tumor cells selectively affected by natural flavonoids and synthetic derivatives

Cancer Therapy - Tumor-inhibitory neural progenitor cells can be targeted to gliomas

Cancer Therapy - U.S. FDA grants marketing approval to Valeant for cannabinoid oral capsules to treat nausea

Cancer Vaccine - Advaxis continues advancement of listeria vaccines targeting cancers affecting women

Cancer Vaccine - Antigen delivery to antigen-presenting cells using penetratin induces potent immune responses

Cancer Vaccine - DNA-based cancer vaccine enhances lymphocyte cross-talk by engaging NKG2D receptor

Cancer Vaccine - Double loading of dendritic cells with AML antigen enhances T cell immunity

Cancer Vaccine - Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates has been developed for cancer vaccine

Cancer Vaccine - ITAC vaccination attenuates disseminated metastases of circulating tumor cells

Cancer Vaccine - MUC1/IL-18 DNA vaccine induces antitumor immunity and increased survival

Cancer Vaccine - New assays for immune monitoring in cancer vaccine development are needed

Cancer Vaccine - Regulatory considerations for nonclinical cancer vaccine development are discussed

Carcinogenesis - Cancer growth linked to disruption of circadian coordination

Carcinogenesis - Chemopreventive effect of punicalagin investigated

Carcinoid Cancer Therapy - EntreMed initiates combination Phase 2 clinical trial with Panzem NCD in carcinoid cancer

Cardiovascular Research - Mortality risks are associated with zinc, copper, and magnesium levels

Cell Biology - Radiation-related capillary damage may involve endothelial cell apoptosis

Cervical Cancer - Cervical cancer angiogenesis and immunology are altered by celecoxib

Cervical Cancer - DNA hypermethylation patterns analyzed in different types of uterine cancer

Cervical Cancer - New study reports on improved disease detection with the ThinPrep Imaging System

Cervical Cancer - Norwegian cervical carcinoma patients presented with human papillomavirus E6 and E7 mRNA

Chemotherapy - Intensified chemotherapy is facilitated by retroviral-mediated chemoprotection

Chest Wall Tumors - Unusual case of grass inflorescence aspiration presented as chest wall tumor

Clinical Trials - Threshold Pharmaceuticals reports changes to TH-070 clinical development program

Collaborations - Bioenvision, Mayne Pharma ink marketing, distribution agreement for Evoltra

Colon Cancer - Colon cancer patients' follow-up by surgeons or GPs experience similar outcome

Colon Cancer - Colon cancer risk weakly linked to GSTM1 and GSTT1 polymorphisms

Colon Cancer - EGFR gene mutations in gastrointestinal tract cancer may limit the value of gefitinib

Colon Cancer - Stool testing is a novel technique for detecting colon cancer

Colorectal Cancer - Colorectal adenocarcinoma associated with higher expression of NMT2

Colorectal Cancer - Colorectal cancer nucleotide and base excision repair gene polymorphisms clarified

Colorectal Cancer - Colorectal cancer patient response to 5-FU-based chemotherapy not predicted by MTHFR genotype

Colorectal Cancer - Colorectal cancer progression is denoted by VEGF in patients given post-operative fluoropyrimidines

Colorectal Cancer - Colorectal cancer treatment with fixed-dose capecitabine is effective

Colorectal Cancer - Colorectal carcinogenesis linked to increased expression of claudin-2

Colorectal Cancer Vaccine - CD137 and CD137 ligand expression in colorectal cancer are focus of review

Contracts - North American Scientific signs agreement with Novation for Prospera brachytherapy sources

Cytomegalovirus - Cytomegalovirus IE2-86 protein binds mdm2 and facilitates mdm2 degradation

Developmental Biology - Integrin maturation promoted by beta 1,4-galactosyltransferase down-regulation

Diagnostics - Adenoid cystic carcinomas distinguished from cylindromatous adenomas by Ultrafast Papanicolaou

Diagnostics - Cholangiocarcinomas differentiated from benign cholangiocellular lesions by CD56 expression

Diagnostics - Differentiating enchondroma from secondary chondrosarcoma in the foot is difficult

Diagnostics - Head and neck cancer differentiated from leukoplakia by cytokeratin 8 expression

Diagnostics - Pilocytic astrocytoma differentiated from medulloblastoma by T2-weighted imaging

Disease Associations - Incidence of second cancers increased among breast cancer patients

Drug Development - Breast cancer exposed to antiproliferative effects of fish protein hydrolysates

Drug Development - Combretastatin nitrogen-containing derivatives developed as vascular disrupting agents

Drug Development - Dendreon presents data on potential new active immunotherapy for treating renal cell cancer

Drug Development - Dyax provides update on regulatory pathway for DX-88; Phase III trial on track to complete 2H06

Drug Development - Idera broadens toll-like receptor programs, presents new data

Embryonic Stem Cell Research - Cerberus 1 is common WNT and NODAL signaling pathway target in embryonic stem cells

Endometrial Cancer - Endometrial cancer function modulated by estrogen-related receptor alpha

Endometrial Cancer - Endometrioid carcinoma poor prognosis linked to elevated ezrin expression

Epidermal Cancer - Mucoepidermoid carcinomas classified on molecular basis of an MECT1-MAML2 fusion

Esophageal Adenocarcinoma - Early esophageal adenocarcinoma detection and use of nonsurgical treatments may improve outcome

Finance - Allostera Pharma closes final seed financing round

Finance - CytoCore announces major institutional investor converts note to stock

Finance - Leukemia & Lymphoma Society awards over $400,000 to Texas centers serving hurricane victims

Finance - MacroGenics raises $45 million in series C financing

Finance - NeoRx Corporation reports first quarter net loss of $5.8 million

Finance - OncoMethylome Sciences announces plans for Euronext listing in Brussels and Amsterdam

Gallbladder Cancer - Gallbladder carcinoma evaluation by delayed F-18-FDG PET preferred

Gastric Cancer - Gastric cancer morbidity was low after extended lymph node dissection

Gastric Cancer - Gastric cancer prognosis linked to matrix metalloproteinase-2

Gastric Cancer - Gastric cancer progression and carcinogenesis affected by loss of heterozygosity

Gastric Cancer - Gastric cancer treatment by intraarterial chemotherapy offers no survival benefit

Gastric Cancer - Perforation induced by endoscopic resection of gastric cancer prevented surgery

Gastric Cancer - Recommended doses for phase II study with paclitaxel and S-1 in gastric cancer listed

Gastric Cancer - Risk of gastric cancer mortality may be reduced by screening

Gastrointestinal Cancer - Genomic damage in gastrointestinal cancers may be preceded by age-dependent DNA demethylation

Gastrointestinal Cancer - Lewis(Y) antigen not significantly linked to apoptosis in gastric and colorectal carcinomas

Genetics & Genomics - PRAF2 genomic organization and expression characterized

Germ Cell Cancer - Dysgerminoma distinguished from nongerm cell malignancies by chromosome 12p abnormalities

Glioma - Glioma angiogenesis is thwarted by the cough suppressant noscapine

Glioma - Glioma models show thalidomide enhances the effect of radiosurgery

Glioma - Gliomas thrive when prolonged hypoxia triggers proangiogenic signals

Glioma - Malignant glioma may be stopped by dominant-negative inhibition of Axl

Glioma - Testes-specific, vespid, and pathogenesis protein 1 proposed as therapeutic target in gliomas

Head & Neck Cancer - Head and neck cancer patients should receive long-term care after external beam irradiation

Head & Neck Cancer - Head and neck tumor cell survival may be affected by CXC chemokine receptor 4

Head & Neck Cancer - Lymph node status in squamous cell carcinoma is reflected by cytokeratin 19 mRNA

Head & Neck Cancer - Second primary tumors in head and neck cancer patients not prevented with low-dose isotretinoin

Healthcare Access - Cancer patients need help finding medical information, study finds

Hematopoiesis - Lack of alpha 4 integrin expression in stem cells restricts competitive function and self-renewal

Hepatic Hilar Cholangiocarcinoma - Hepatic hilar cholangiocarcinoma resectability assessed by combined CT and cholangiography

Hepatic Neuroendocrine Tumors - Primary hepatic neuroendocrine tumor treatment options discussed

Hepatitis B Virus - HBV HBx protein activation of focal adhesion kinase functions in carcinogenesis

Hepatitis C Virus - HCV-associated lymphoproliferative disorders involve interleukin inhibitors

Hepatitis C Virus - Hepatitis C virus cyclophilin inhibitors exert novel effects

Hepatocellular Cancer - Hcc-2 is an ER thioredoxin that is differentially expressed in hepatocellular carcinomas

Hepatocellular Cancer - Hepatocellular cancer malignancy linked to reduced copy number of mitochondrial DNA

Hepatocellular Cancer - Hepatocellular cancer treatment by pretransplant locoregional hepatic therapy lacks benefit

Hepatocellular Cancer - New prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

Hepatocellular Carcinoma - HCC and non-tumorous tissues microRNA expression patterns determined

High Cholesterol - PhytoMedical's BDC-O3 compound shown to elevate HDL levels in blood

Hodgkin Lymphoma - Hodgkin lymphoma staged accurately with position emission tomography with computed tomography

Human Papillomavirus Vaccine - Efficiency of HPV 16 L1/E7 DNA immunization is reported

Human Papillomavirus Vaccine - Improved HPV DNA vaccine candidate induces a wild-type-specific T cell response

Human Papillomavirus Vaccine - Parental acceptance of adolescent HPV vaccine is critical for success

Hypopharyngeal Cancer - Hypopharyngeal cancer detected early with periodic endoscopic screening

Imaging - Multi-tracer PET imaging reveals tumor response to pan-Erb-B inhibitor CI-1033

Imaging - Virally directed fluorescent imaging can facilitate endoscopic staging

Immunotherapy - Immunogenic anti-CD3 antibody-interleukin-2 fusion protein developed

Laryngeal Cancer - Inflammatory myofibroblastic larynx tumor indicators described

Laryngeal Cancer - Laryngeal cancer cell growth is compromised by elemene

Leukemia - Acute leukemia linked to JARID1A, a new partner gene

Leukemia - Advances in childhood acute myeloid leukemia reviewed

Leukemia - Leukemia immunophenotypic scoring system proposed

Leukemia - Leukemia prognosis after induction therapy predicted by high WT1 expression

Leukemia - Molecular-based mechanism for restriction of leukemic phenotype to CD4+ T cell subtype described

Leukemia - Murine models of human juvenile myelomonocytic leukemia used to explore novel therapies

Leukemia - Novel GFP-based ratiometric excitation and emission pH indicator developed

Leukemia Vaccine - Enhanced sensitivity to SHP2, STAT5, and Gab2 inhibition were found in chronic myeloid leukemia

Lewis Lung Cancer - Muscle mass in mice with Lewis lung carcinoma preserved with conjugated linoleic acid

Licensing Agreements - Abbott enters deal with Advanced Life Science Institute to develop lung cancer test

Liver Cancer - Study finds radioactive microspheres prolong survival in metastatic liver cancer patients

Lung Cancer - Diagnostic agreement in evaluation of lung cancer tissue complicates epidemiology studies

Lung Cancer - Lung cancer apoptosis induced by OSU03013 via the mitochondrial pathway

Lung Cancer - Lung cancer associated with tumor necrosis factor-alpha polymorphisms

Lung Cancer - Lung cancer cell death induced by chloroquine diphosphate

Lung Cancer - Lung cancer survival prognosticated by bone marrow hypermetabolism

Lung Cancer - Lung cancer was heralded by inflammatory sternal metastasis

Lung Cancer - Lung fiber burden in lung cancer patients employed in the rock and slag wool industry analyzed

Lung Cancer - Lung resection is performed in many patients with benign disease

Lung Cancer - Non-small cell lung cancer risk heightened in carriers of TP53 gene mutations

Lung Cancer - Phase II study dose recommendations for 3-day topotecan and cisplatin in lung cancer listed

Lung Cancer - Trial of lung cancer treatment with tri-weekly paclitaxel combined with carboplatin warranted

Lung Cancer Therapy - Pharmacodynamic assay for farnesyl transferase inhibitors has been developed

Lung Cancer Vaccine - Cancer-testis antigens show promise for non-small cell lung cancer therapeutics

Lung Cancer Vaccine - Foxp3 expression is higher in lung cancer than in normal tissues

Lymphoma - Lymphoma cannot be reliably diagnosed by intrasinusoidal infiltration quantity

Male Breast Cancer - Male and female breast cancer exhibit hormonal differences

Melanoma - Malignant melanoma treated by hepatic resection in selected patients

Melanoma - Simple digital image processing system to aid in melanoma diagnosis developed

Melanoma - The melanoma staging system from the American Joint Commission on Cancer is evaluated

Melanoma Vaccine - Allogeneic and autologous melanoma vaccines are the focus of review

Melanoma Vaccine - Cytokine-based therapy for advanced melanoma is the focus of review

Melanoma Vaccine - Immunosuppression in melanoma immunotherapy offers intervention opportunities

Melanoma Vaccine - Melanoma vaccines must boost immune response and prevent tumor cell evasion

Melanoma Vaccine - Overcoming immune resistance mechanisms in melanoma microenvironment is discussed

Memory T Cells - T cell lymphocyte-associated antigen identified on skin-homing helper memory T cells

Meningioma - HER2 overexpression represented an independent prognostic factor in meningiomas

Mergers & Acquisitions - Diatos announces acquisition of specialty cancer product DaunoXome from Gilead Sciences

Mesorectal Tumors - Rectal cancer prognosis predicted by extent of mesorectal tumor invasion

Mesothelioma - Benign peritoneal cystic mesothelioma could be treated by surgical resection

Metastatic Melanoma - Provectus announces a second group of patients treated in phase I trial of PV-10

Multiple Myeloma - Higher age adversely influences intensive therapy outcome in multiple myeloma

Natural Products - Analysis of onion and garlic relating to common diseases is reviewed

Nontraumatic Osteonecrosis - Risk factors identified for MSC differentiation alterations in nontraumatic osteonecrosis

Oncology - Cancer cells escape immunological attack with the aid of semaphorin-3A

Oncology - Cancer screening behaviors are not influenced by an intervention program

Oncology - Metastasis promotion or inhibition is a function of enzyme proteolysis

Oncology - Tumor angiogenesis requires ELF-1 signals

Oral Cancer - Oral cancer progression is defeated when iCaspase-9 targets tumor angiogenesis

Oral Cancer - Oral squamous cell carcinoma risk heightened by low body mass index

Oral Squamous Cell Carcinoma - Oral squamous cell carcinoma metastasis linked to expression of RAD21 gene

Oropharyngeal Squamous Cell Carcinoma - Oropharyngeal squamous cell carcinoma histopathological prognosticators listed

Ovarian Cancer - Drug-resistant ovarian cancer is predicted by RhoGDI

Ovarian Cancer - Ovarian adenocarcinoma distinguished from autoimplants in serous borderline tumors

Ovarian Cancer - Ovarian cancer apoptosis induced by epigallocatechin-3-gallate

Ovarian Cancer - Platinum-treated ovarian cancer patients managed with epoetin alfa

Ovarian Cancer - U.S. FDA grants orphan drug status to combretastatin A4P for treating ovarian cancer

Pancreatic Adenocarcinoma - Pancreatic adenocarcinoma diagnosis improved by measuring telomerase activity

Pancreatic Cancer - Pancreatic ductal adenocarcinoma is identified by excess phosphoglycerate kinase 1

Pancreatic Cancer - Refractory pancreatic cancer patients are treated with liposomal cisplatin and gemcitabine

Pancreatic Cancer - Solid pancreatic masses treated by EUS-FNA infrequently linked to major complications

Pancreatic Cancer - Unresectable pancreatic carcinoma treated by gemcitabine and docetaxel

Papillary Thyroid Cancer - Papillary thyroid cancer treated by lymphadenectomy

Patents - Endocyte announces patent issued to enhance cancer-targeting in immunotherapy

Patents - Euroscreen receives key patent for purinergic receptor

Patient Care - Cancer patients who are outside the informal support system in hospitals may benefit from home care

Pediatric Oncology - Adolescent/young adult cancer outcomes should be studied to optimize management

Pediatric Oncology - Childhood cancer survivors in early adulthood have higher risk of posttraumatic stress disorder

Pediatric Oncology - Further study of posttraumatic growth after childhood cancer is warranted

Pediatric Oncology - Survivors of childhood cancer often face unemployment hardship

Peripheral Nerve Sheath Tumors - Peripheral nerve sheath tumors linked to aberrant expression of CHFR

Personnel - Cephalon appoints Ambassador Kevin E. Moley to board of directors

Personnel - Dr. Christopher Lipinski to advise Medisyn Technologies on pharma industry opportunities

Personnel - IBEX reappoints Robert Heft to board

Personnel - ImClone names Elizabeth Yamashita vice president, regulatory CMC and operations

Personnel - John Gutheil, MD, named chief medical officer, senior VP of clinical affairs by Proacta

Personnel - Pharmion appoints Andrew Allen as chief medical officer

Personnel - Seattle Genetics names Pamela Trail, PhD, as chief scientific officer

Personnel - Sonus CMO Michael B. Stewart retires; Elaine Waller, Richard Daifuku assume new duties

Pharmaceutical Research - Thalidomide targets direct and indirect elements of blood vessel formation

Pharmacology - Fractionated urine samples can replace 24-hour urine collection to evaluate platinum concentrations

Pharyngeal Cancer - Pharyngeal carcinoma health-related quality of life at diagnosis predicted prognosis over time

Philanthropy - Florida-based Keiser College students raise over $21,500 for American Cancer Society

Philanthropy - National Cancer Coalition participates in cancer medicine airlift to Belarus

Philanthropy - Oreck Corporation partners with Susan G. Komen Breast Cancer Foundation to raise funds

Preventive Medicine - Study provides road map to preventive services with greatest health impact, best cost value

Product Licensing - Inovio acquires rights to augment patent estate for electroporation-assisted nucleic acid delivery

Product Licensing - Oncotech to market Innocell's cancer diagnostic services in South Korea

Prostate Cancer - Cell Genesys receives Fast Track status for GVAX immunotherapy for prostate cancer

Prostate Cancer - Chronic Disease Score was the easiest and most useful comorbidity index for prostate cancer

Prostate Cancer - HIFU prostate cancer study begins

Prostate Cancer - Men considering hypothetical treatment for prostate cancer interviewed

Prostate Cancer - Prostate cancer hormonal progression is prevented by targeting androgen receptor domain

Prostate Cancer - Prostate cancer invasion is suppressed by the non-genomic effects of a vitamin D analogue

Prostate Cancer - Prostate cancer screening aided by educational materials for shared decision-making

Proteomics - Nidogen and TEM7 interactions support angiogenesis

Pulmonary Cancer - Small peripheral pulmonary adenocarcinoma growth pattern correlated with fluorodeoxyglucose uptake

Rectal Cancer - Early rectal cancer treated with TEM only is associated with a recurrence risk

Rectal Cancer - Lower rectal cancers can be removed by laparoscopic abdominoperineal resection

Rectal Cancer - Rectal cancer associated with considerable local recurrence after surgery

Rectal Cancer - Rectal cancer staged accurately with 3-Tesla magnetic resonance imaging

Rectal Cancer - Rectal cancer treated by chemoradiation with capecitabine and weekly irinotecan

Renal Cell Carcinoma - Large renal cell cancers treated by radiofrequency ablation plus renal arterial embolization

Renal Cell Carcinoma - Promising early results seen with adjuvant treatments for renal cell carcinoma

Renal Cell Carcinoma - Renal cell carcinoma pathogenesis not linked to promoter hypermethylation

Renal Cell Carcinoma - Vascular dynamics of renal cell carcinoma are depicted on computed tomography

Sexual & Reproductive Health - Colposcopy improves detection of post-treatment cervical intraepithelial neoplasia

Sexual & Reproductive Health - Hypertension may be associated with endometrial thickening

Sexual & Reproductive Health - Hysterectomy appears best treatment for women with atypical endometrial hyperplasia

Sickle Cell Anemia - Advances in management of sickle cell disease reviewed

Skin Cancer - Melanoma - the deadliest skin cancer - is on the rise in the United States

Solid Tumors - Spectrum starts phase 1 trial to evaluate satraplatin plus capecitabine in solid tumors

Spine Surgery - Metastatic spine surgery does not benefit from tranexamic acid

Squamous Cell Carcinoma - Characteristics and outcome of non-squamous cell malignancies of maxillary sinus described

Squamous Cell Carcinoma - Esophageal and cardia adenocarcinoma classification needs readdressing to optimize treatment

Squamous Cell Carcinoma - Esophageal squamous cell carcinoma chemosensitivity predicted

Squamous Cell Carcinoma - Esophageal squamous cell carcinomas display different gene expression profiles

Squamous Cell Carcinoma - Oropharyngeal squamous cell carcinoma diagnosis delay linked to poorer survival

Squamous Cell Carcinoma - Squamous cell carcinomas of the lung prognosticated by minimal tumor nest size

Stem Cell Transplantation - AHSCT-related mortality in chronic myeloid leukemia declined from 1990 to 2004

Stem Cell Transplantation - Hematopoietic stem/progenitor cell engraftment enhanced by transient Lnk inhibition

Stem Cell Transplantation - Oral valganciclovir leads to higher ganciclovir exposure than IV ganciclovir after SCT

Stem Cell Transplantation - Reduced intensity allogeneic stem cell transplantation successful in systemic AL amyloidosis

Thyroid Cancer - Differentiated thyroid cancer diagnosis improved with integrated PET/CT

Thyroid Cancer - Early thyroid cancers are marked by coexpressed enzymes

Thyroid Cancer - Focal thyroid lesions incidentally found on 18F-FDG PET/CT have a high risk of thyroid malignancy

Thyroid Cancer - Risk factors for thyroid cancer recurrence after surgery identified

Thyroid Cancer - Thyroid carcinoma radioiodide uptake is increased by bexarotene

Tubulolobular Cancer - Tubulolobular carcinoma of the breast may not be a variant of lobular carcinoma

Urothelial Cancer - High-grade urothelial carcinoma of renal pelvis displays unusual morphologic features

Apoptosis - Researchers from the United States, United Kingdom and Japan provide details of new studies and findings in the area of apoptosis

Biomedical Engineering - New findings from Japan and the South Korea in the area of biomedical engineering described

Breast Cancer - Data from Italy and the United States advance knowledge in breast cancer research

Breast Cancer - Data from the United Kingdom, and United States advance knowledge in breast cancer research

Breast Cancer - Findings from Japan and the United Kingdom describe new data in breast cancer research

Breast Cancer - Findings from the United States, Spain and Italy advance knowledge in breast cancer research

Breast Cancer - New data from Spain, Germany and the United States lluminates research in breast cancer

Breast Cancer - New research from Scotland and the United States in the area of breast cancer detailed

Breast Cancer - Recent studies from the United Kingdom, Japan and United States add new data to breast cancer research

Breast Cancer - Reports from the People's Republic of China, United States and Sweden add new data to breast cancer research

Breast Cancer - Reports from the United States and France advance knowledge in breast cancer research

Breast Cancer - Research from the United Kingdom and United States add new data to breast cancer body of knowledge

Breast Cancer - Research from the United States and South Korea in breast cancer provides new insights

Breast Cancer - Researchers from France, Switzerland and the United Kingdom describe findings in breast cancer studies

Breast Cancer - Researchers from Russia and the United States report details of new studies and findings in the area of breast cancer

Breast Cancer - Researchers from the United Kingdom and United States report recent findings in breast cancer

Breast Cancer - Researchers' data from the United Kingdom, Japan and Germany advance breast cancer research

Breast Cancer - Studies from Spain, the United Kingdom and Italy advance knowledge in breast cancer research

Breast Cancer - Studies from the People's Republic of China, United Kingdom and United States add new findings to breast cancer body of knowledge

Breast Cancer - Studies from the United States, France and Italy describe new findings in breast cancer research

Cancer Research - New findings from the United States and Japan in the area of cancer described

Cancer Research - New findings in cancer described from Canada, Japan and the United States

Cancer Research - Researchers from France, Italy and the United States detail new studies and findings in the area of cancer

Cancer Research - Researchers' findings from the United States and Austria advance cancer research

Cancer Research - Studies from Japan and the South Africa describe new findings in cancer research

Cancer Treatment - Findings from the United States advance knowledge in cancer treatment research

Cancer Treatment - New data from Japan and the United States lluminates research in cancer treatment

Cancer Treatment - New data from the United States, Netherlands and United Kingdom lluminates research in cancer treatment

Cancer Treatment - New findings from Australia, Japan and Netherlands in the area of cancer treatment detailed

Cancer Treatment - New findings from the United States, People's Republic of China and Israel in the area of cancer treatment described

Cancer Treatment - New research from Netherlands and United States in the area of cancer treatment detailed

Cancer Treatment - New research from the United States and NORTH Ireland in the area of cancer treatment detailed

Cancer Treatment - Recent findings from the United States and Germany illuminate research in cancer treatment

Cancer Treatment - Recent findings in cancer treatment described by researchers from Japan, the People's Republic of China and Sweden

Cancer Treatment - Reports from the Netherlands, Japan and Germany describe recent advances in cancer treatment research

Cancer Treatment - Reports from the United States and Japan add new data to cancer treatment research

Cancer Treatment - Research from South Korea, People's Republic of China and United Kingdom add new data to cancer treatment body of knowledge

Cancer Treatment - Research from the People's Republic of China, Spain and Denmark in cancer treatment provides new insights

Cancer Treatment - Researchers from Belgium, China and Japan provide details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Germany, Japan and the United States describe findings in cancer treatment studies

Cancer Treatment - Researchers from Italy, the United Kingdom and the United States provide details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from Japan, Switzerland and Germany report recent findings in cancer treatment

Cancer Treatment - Researchers' data from the United States and Brazil advance cancer treatment research

Cancer Treatment - Researchers' findings from the United States advance cancer treatment research

Cancer Treatment - Studies from Switzerland, Austria and Israel add new findings to cancer treatment body of knowledge

Cell Biology - New research from Germany, the United Kingdom and Denmark in the area of cell biology detailed

Cervical Cancer - Reports from Italy, the United Kingdom and Austria add new data to cervical cancer research

Colon Cancer - Studies from Scotland, the United States and Netherlands describe new findings in colon cancer research

Colorectal Cancer - Findings from France, the United States and Scotland in colorectal cancer provide new insights

Colorectal Cancer - New findings in colorectal cancer described from Greece, Canada and Argentina

Colorectal Cancer - New research from South Korea, Poland and United States in the area of colorectal cancer detailed

Cord Blood - Researchers from the United States provide details of new studies and findings in the area of cord blood

Diagnostics - Reports from the United States and Japan advance knowledge in diagnostics research

Diagnostics - Researchers' data from Japan, Germany and Netherlands advance diagnostics research

Esophageal Cancer - Researchers from Japan, Turkey and Sweden provide details of new studies and findings in the area of esophageal cancer

Gastroenterology - Recent findings from Sweden and the United States illuminate research in gastroenterology

Genetics - Studies from Netherlands and United States advance knowledge in genetics research

HIV/AIDS - Reports from the United States and United Kingdom advance knowledge in HIV/AIDS research

Head & Neck Cancer - Findings from Italy, the United States and the People's Republic of China describe new data in head & neck cancer research

Head & Neck Cancer - Researchers' work from the United States, Japan and Brazil adds to head & neck cancer body of knowledge

Head & Neck Cancer - Studies from Germany, Greece and Singapore add new findings to head & neck cancer body of knowledge

Hepatitis C Virus - Recent findings in hepatitis C virus described by researchers from the United States and Poland

Hepatocellular Carcinoma - Recent findings from Japan and Taiwan illuminate research in hepatocellular carcinoma

Hepatocellular Carcinoma - Recent findings in hepatocellular carcinoma described by researchers from Taiwan, Japan and the United States

Hepatocellular Carcinoma - Recent studies from the People's Republic of China, Italy and Japan add new data to hepatocellular carcinoma research

Hepatocellular Carcinoma - Reports from Japan and the United States add new data to hepatocellular carcinoma research

Hepatocellular Carcinoma - Research from the People's Republic of China, France and Taiwan in hepatocellular carcinoma provides new insights

Hepatocellular Carcinoma - Researchers from the People's Republic of China and Taiwan describe findings in hepatocellular carcinoma studies

Hepatocellular Carcinoma - Researchers from the United States, Germany and Spain report recent findings in hepatocellular carcinoma

Herpes - Findings from the United States and Japan describe new data in herpes research

Imaging - New data from the United States and France lluminates research in imaging

Imaging - Reports from Netherlands, United States and People's Republic of China add new data to imaging research

Leukemia - New data from Germany and Switzerland lluminates research in leukemia

Leukemia - Recent findings in leukemia described by researchers from the United States, People's Republic of China and Japan

Leukemia - Reports from the United States, Japan and Scotland add new data to leukemia research

Leukemia - Research from Thailand, Germany and Belgium in leukemia provides new insights

Leukemia - Researchers from the United States, People's Republic of China and Germany describe findings in leukemia studies

Leukemia - Researchers' work from the United Kingdom, United States and Italy adds to leukemia body of knowledge

Liver Cancer - Reports from the United States and Germany advance knowledge in liver cancer research

Liver Cancer - Research from the People's Republic of China, Australia and Japan add new data to liver cancer body of knowledge

Lung Cancer - Data from France, Italy and the United States advance knowledge in lung cancer research

Lung Cancer - New data from the United States and Japan lluminates research in lung cancer

Lung Cancer - New findings from Netherlands, United States and United Kingdom in the area of lung cancer detailed

Lung Cancer - New findings from Switzerland, Japan and the United States in the area of lung cancer described

Lung Cancer - New findings in lung cancer described from South Korea, People's Republic of China and United States

Lung Cancer - New research from Spain, France and Greece in the area of lung cancer detailed

Lung Cancer - Reports from Mexico, Japan and Germany add new data to lung cancer research

Lung Cancer - Researchers from Italy and France report recent findings in lung cancer

Lung Cancer - Studies from Italy, the United States and Japan add new findings to lung cancer body of knowledge

Lymphoma - Researchers' data from the United States advance lymphoma research

Lymphoma - Studies from the United Kingdom and France describe new findings in lymphoma research

Melanoma - Researchers' data from the United States and Germany advance melanoma research

Melanoma - Researchers' findings from the United States and Denmark advance melanoma research

Myeloma - Reports from the United States and Spain advance knowledge in myeloma research

Neurology - Researchers' data from South Korea and Japan advance neurology research

Oncology - Research from the United Kingdom, Canada and Italy in oncology provides new insights

Oncology - Researchers from the United States and Japan detail new studies and findings in the area of oncology

Pancreatic Cancer - Recent findings from Italy, Switzerland and Germany illuminate research in pancreatic cancer

Papillomavirus - Reports from Germany, Netherlands and the United States advance knowledge in papillomavirus research

Prostate Cancer - New findings from Canada and the United States in the area of prostate cancer detailed

Prostate Cancer - Recent findings in prostate cancer described by researchers from the United States

Prostate Cancer - Reports from the United States and Switzerland advance knowledge in prostate cancer research

Proteins - Reports from Sweden, the United States and Netherlands advance knowledge in proteins research

Renal Cancer - Recent findings in renal cancer described by researchers from Italy, Germany and Sweden

Surgery - Findings from Japan and the United States describe new data in surgery research

Transplants - Studies from Japan, the United States and the United Kingdom add new findings to transplants body of knowledge

Vaccines - Research from Austria, Iceland and the United States add new data to vaccines body of knowledge

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