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Metastatic Melanoma

Provectus announces a second group of patients treated in phase I trial of PV-10

Published in Cancer Weekly, June 12th, 2006

Provectus Pharmaceuticals, Inc. (PVCT) announced that a second group of subjects has been treated in the company's phase I clinical trial of PV-10 (also known as Provecta) for ablation of metastatic melanoma, an aggressive and often fatal form of skin cancer.

Treatment with PV-10 was well tolerated by all subjects, with no evidence of systemic or serious local side effects. Most subjects have exhibited evidence of efficacy, ranging from tumor shrinkage to complete ablation. Several also exhibited subsequent shrinkage of untreated tumors, a response characteristic of the "bystander effect." These results achieve the primary study endpoints of safety and preliminary...

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