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Colorectal Cancer

Findings from France, the United States and Scotland in colorectal cancer provide new insights

Published in Cancer Weekly, June 12th, 2006

Reports from France, the United States and Scotland highlight recent research in colorectal cancer.

Study 1: Colorectal cancer was associated with IFITM gene expression.

"We analyzed the expression profiles of intestinal adenomas from a new murine familial adenomatous polyposis model (Apc(Delta 14/+)) using suppression subtractive hybridization to identify novel diagnostic markers of colorectal carcinogenesis. We identified 18 candidate genes having increased expression levels in the adenoma," investigators in France reported.

"Subsequent Northern blotting, real-time reverse transcription-PCR, and in situ hybridization analysis...

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