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Lung Cancer

Lung cancer genetic abnormalities detected by FISH analysis

Published in Cancer Weekly, June 27th, 2006

Lung cancer genetic abnormalities could be detected by fluorescence in situ hybridization (FISH) analysis.

According to recent research from Austria, "Detection of molecular abnormalities could provide an essential tool for the diagnosis of non-small cell lung cancer (NSCLC) and defining patients at risk for early relapse. FISH targeting 17 gene loci was applied to determine the frequency of molecular alteration in NSCLC probes and adjacent tumour-free bronchial epithelium."

"FISH was performed on fresh frozen specimens from 76 patients with histologically confirmed NSCLC and 54 specimens of adjacent tumour-free tissue," explained W. Hilbe and...

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