Published in Cancer Weekly, July 11th, 2006
According to recent research from the United States, "MPNSTs occur most frequently in patients with neurofibromatosis type 1 and are often fatal. Current therapy relies upon radical surgical resection, which often fails to completely remove the tumor."
"To address the need for novel treatment approaches for this disease, we sought to determine if human MPNST-derived cell lines are sensitive to oHSV infection. Activation of the Ras pathway and its inhibitory effects on protein kinase R (PKR)...
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