Leukemia
Leukemia developed in patient with primary thrombocythemia and absence of BCR/ABL rearrangement
Published in Cancer Weekly, July 25th, 2006
According to recent research published in the journal Cancer Genetics and Cytogenetics, "A 65-year-old woman presented with clinical features of PT, and absence of the BCR/ABL fusion gene. She responded to hydroxyurea treatment, although after 1 year she required progressive increases in the dose."
"Six years later, she maintained a high platelet count despite hydroxyurea at 2 g/day and treatment was changed to anagrelide. After 3 weeks, both platelet and leukocyte counts increased. A karyotype study detected the Philadelphia...
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Source: Cancer Weekly (2006-07-25)
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