Published in Cancer Weekly, August 8th, 2006
"The proto-oncogene c-Myc plays a central role in cell growth and the development of human tumors. c-Myc interacts with Max and Myc-Max complexes bind to E-box and related sequences to activate transcription. Max also interacts with Mnt but Mnt-Max complexes repress transcription when bound to these sequences," wrote K. Toyooka and colleagues, University California San Diego.
"MNT maps to human chromosome 17p13.3, a region frequently deleted in various human tumors, including...
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