Cancer Research
New data from Sweden, the United States and Canada lluminates research in cancer
Published in Cancer Weekly, August 8th, 2006
Study 1: According to recent research from Sweden, adenovirus-mediated CD40 ligand (CD40L) therapy induces tumor cell apoptosis and systemic immunity in the TRAMP-C2 mouse prostate cancer model.
"The interaction between CD40 ligand (CD40L) and CD40 on antigen presenting cells is essential for the initiation of antigen-specific T-cell responses, whereas CD40L stimulation of CD40+ tumor cells can induce cellular apoptosis. We investigated the anti-tumor effects induced by CD40L gene transfer into the mouse prostate adenocarcinoma cell line TRAMP-C2, both in vitro and in...
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Source: Cancer Weekly (2006-08-08)
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