Breast Cancer
Breast cancer invasiveness linked to low glucose levels
Published in Cancer Weekly, August 15th, 2006
"Glucose deprivation has been shown to increase the invasive and metastatic potential of tumor cells. In the present study, we determined whether the enhanced tumor cell invasiveness resulting from glucose deprivation is linked to increased activity of enzymes required for extracellular matrix degradation," investigators in Canada reported.
"Results of in vitro invasion assays revealed that the invasiveness of human MDA-MB-231 and MCF-7 breast carcinoma cells and MCF-10A1 normal breast cells was,...
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Source: Cancer Weekly (2006-08-15)
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