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Bladder Cancer

Recurrence-free survival prognosticated by lymph node density

Published in Cancer Weekly, August 15th, 2006

Lymph node density could be used to prognosticate recurrence-free survival cancer patients, even when adjuvant chemotherapy was used.

According to a study from the United States, "Lymph node density, that is the ratio of positive nodes to the total number of nodes excised, has been suggested to better stratify patients with bladder cancer who have nodal metastasis. We evaluated its relevance in a contemporary series of patients treated with radical cystectomy and in the context of adjuvant chemotherapy. From 1993 to 2003, 150 patients had pN+MO disease at cystectomy, of whom 108 who did not receive neoadjuvant chemotherapy form the basis of this reported."

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