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Cancer Therapy

Tumor angiogenesis in cancer models is prevented by a cannabinoid quinone

Published in Cancer Weekly, August 22nd, 2006

Tumor angiogenesis in cancer models is prevented by a cannabinoid quinone.

According to recent research from Israel, "Recent findings on the inhibition of angiogenesis and vascular endothelial cell proliferation by anthracycline antibiotics, which contain a quinone moiety, make this type of compound a very promising lead in cancer research/therapy. We have reported that a new cannabinoid anticancer quinone, cannabidiol hydroxyquinone (HU-331), is highly effective against tumor xenografts in nude mice."

"For evaluation of the antiangiogenic action of cannabinoid quinones, collagen-embedded rat aortic ring assay was used. The ability of cannabinoids to...

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