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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . September 5th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Childhood Cancer - Adult survivors of childhood cancer may be at risk of unemployment

Head & Neck Cancer - Head and neck squamous cell carcinoma risk reduced in smokers and drinkers by dietary antioxidants

Mental Health - Adults with serious mental illness have elevated cancer incidence

Prostate Cancer - Prostate cancer patients assessed for anxiety by Memorial Anxiety Scale for Prostate Cancer

Acid Reflux - Researchers discover how acid reflux leads to esophageal cancer

Acute Myeloid Leukemia - Dacogen (decitabine) for Injection receives U.S. orphan drug designation for patients with AML

Acute Myeloid Leukemia - Positive phase II study of Bcl-2 antisense plus gemtuzumab ozogamicin reported

Adenoid Cystic Cancer - Adenoid cystic carcinoma could present in extra-salivary gland sites

Adrenocortical Hyperplasia - Adrenocortical hyperplasia linked to mutations in phosphodiesterase 11A4 gene

Apoptosis - A new erythroblastic leukemia cell line revealed

Apoptosis - Adenovirus early region 4 ORF4 protein kills cancer cells via rho GTPase-dependent actin dynamics

Apoptosis - Apoptotic pathways are differentially affected by temperature upstream of mitochondrial damage

Assisted Reproduction - Fertility preservation is possible after surgery/chemotherapy for malignant germ cell tumors

Astrocytoma - Astrocytoma angiogenesis patterns do not convey proliferation indices

Awards - David G. Nance receives Albert Einstein Award

Bladder Cancer - Bladder cancer responded to antitumor activity of magainin II

Bladder Cancer - Squamous lesions that are difficult to manage clinically should therapeutically target EGFR

Blood Banking - SYTO 16 dye detects apoptotic lymphocytes and CD34+ cells in cryopreserved cord blood

Bone Tumors - Bone tumors at cranio-cervical junction treated with surgery using lateral approach

Brain Cancer - Brain cancer risk not heightened by low-level exposure to radiofrequency electromagnetic fields

Brain Tumors - Brain tumor patients achieve good functional outcomes with shorter hospital stays

Breast Cancer - A plant that gave ancient Britons and Celts blue war paint is source of an anti-cancer compound

Breast Cancer - ALND followed by continuous local anesthesia infusion holds potential for palliation

Breast Cancer - Bone mineral density is not a reliable prescreening predictor for mammography in women

Breast Cancer - Breast cancer apoptosis mediated by c-Jun-NH2-terminal kinase pathway

Breast Cancer - Breast cancer imaging findings after brachytherapy analyzed

Breast Cancer - Breast cancer in the elderly should be managed with appropriate treatment for prognostics factors

Breast Cancer - Breast cancer invasion suppression requires dimerization of HP1(Hs alpha)

Breast Cancer - Breast cancer patients have different attitudes regarding clinical trials

Breast Cancer - Breast cancer radiotherapy strategies modeled mathematically to predict response

Breast Cancer - Breast cancer survival could not be independently predicted by androgen receptor expression

Breast Cancer - Breast carcinoma and malignant mesothelioma linked to expression of HLA-G

Breast Cancer - Carcinoid tumorlets may resemble pulmonary metastases in women with breast cancer

Breast Cancer - Fatigue, sleep, and depressive symptoms are more prevalent in women with cancer

Breast Cancer - Functional dissection of breast cancer amplicon reveals gene contributions

Breast Cancer - Genetic counseling after breast cancer diagnosis does not raise anxiety levels in women

Breast Cancer - Ki-67 expression found in breast fluid may be biomarker for early cancer detection

Breast Cancer - Long-term fenretinide reduces risk of second breast cancer in premenopausal women

Breast Cancer - New findings offer more complete view of breast cancer gene mutations in U.S. population

Breast Cancer - Radiation therapy following breast-conserving surgery reduces incidence of recurrence

Breast Cancer - Specimen radiography confirms success of MRI-guided breast biopsy

Business & Finance - AP Pharma reports loss of $0.18 per share, phase III trial for APF530 underway

Business & Finance - Ariad records loss of $0.27 per share

Business & Finance - Cell Genesys reports net loss of $27.9 million in second quarter

Business & Finance - Cell Therapeutics reports net loss of $21 million for second quarter

Business & Finance - Chemokine Therapeutics announces second quarter 2006 financial and operating results

Business & Finance - Coley Pharmaceutical Group reports six-month net loss of $16.1 million

Business & Finance - Cytogen reports net income of $7.2 million in second quarter

Business & Finance - Dendreon reports second quarter net loss of $18.8 million

Business & Finance - Digene announces record 2006 fourth quarter and year-end results

Business & Finance - DOV Pharmaceutical, Inc. announces second quarter results

Business & Finance - EDAP TMS S.A. reports second quarter results

Business & Finance - Human Genome Sciences reports Q2 net loss of $61.3 million

Business & Finance - ImmunoGen reports 2006 revenues of $32.1M, provides business update

Business & Finance - Sonus reports net loss for Q2 2006 of $4.9 million, compared to $4.1 million loss a year ago

Business Update - Abeille submits AB-1001 phase III study protocol for U.S. FDA review

Business Update - CytoCore's Dr. Gorodeski has second P2X7 biomarker paper accepted for publication

Business Update - Pittsburgh Life Sciences Greenhouse invests $100,000 in RedPath Integrated Pathology

Business Update - Spectrum Pharmaceuticals reports agreement for ozarelix with Nippon Kayaku for Japan market

Business Update - US Oncology, Molecular Profiling Institute join to create Tissue Banking and Analysis Center

Cancer Gene Therapy - Antiapoptosis function of papillomavirus oncoprotein requires inhibited Bax

Cancer Gene Therapy - Gene activation induced by high intensity focused ultrasound in solid tumors

Cancer Gene Therapy - Malignant brain tumors in young mice were treated with immunogene therapy

Cancer Gene Therapy - Molecular imaging allows monitoring of gene therapy of cancer

Cancer Gene Therapy - Ovarian cancer apoptosis enhanced by ionizing radiation adenoviral vector

Cancer Immunology - Telomere length of CD4+CD25+ T cells are preserved in cancer patients

Cancer Marker - Ri antibodies not associated with paraneoplastic neurological syndromes in cancer

Cancer Mortality - Cancer mortality not significantly increased among radiation workers at Rocketdyne

Cancer Research - Contagious cancer in dogs confirmed, origins traced to wolves centuries ago

Cancer Research - Imprime PGG signaling pathway for tumor killing discovered

Cancer Research - PI3-K/Akt kinase signaling components are expressed in endometrioid-type endometrial neoplasms

Cancer Therapy - Acute myeloid leukemia subcutaneous recombinant human interleukin evaluated

Cancer Therapy - Angiogenesis blocked by sustained expression of early growth response protein

Cancer Therapy - Annexin I regulates cell invasion by signaling through formyl peptide receptors

Cancer Therapy - Antidiarrhea treatment alleviated diarrhea induced by irinotecan hydrochloride

Cancer Therapy - Berkelic acid, isolated from acid mine waste fungal extremophile, demonstrated anticancer potential

Cancer Therapy - Cancer growth is stopped or delayed by double therapy in murine models

Cancer Therapy - Cytotoxic assays developed to screen anticancer agents

Cancer Therapy - First patient undergoes treatment at the new University of Florida Proton Therapy Institute

Cancer Therapy - Lung cancer brain metastases treatment should consider chemotherapy as therapy cornerstone

Cancer Therapy - Moffitt Cancer Center gives exclusive license to Tigris to develop cancer compound

Cancer Therapy - New Taxol prodrugs designed for cancer chemotherapy

Cancer Therapy - Potential implications of flavonoid-induced glutathione depletion for cancer treatment examined

Cancer Therapy - Signaling pathway found which transforms otherwise healthy blood vessels into misshapen vasculature

Cancer Therapy - Stem cell-like glioma cancer cells may hold the key to treating some deadly cancers

Cancer Vaccine - Antigen delivery systems for cancer vaccines using Salmonella have been developed

Cancer Vaccine - CD1d-restricted T cells license B cells to generate cytotoxic antitumor immunity

Cancer Vaccine - Scientists develop biophysical approach to optimize dendritic-tumor cell electrofusion

Carcinogenesis - Liver carcinogenesis linked to accumulation of genetic alterations caused by exposure to nodularin

Carcinogenesis - Mutagenicity of mycotoxin alternariol contributes to its carcinogenicity

Cardiology - Factor V Leiden/prothrombin G20210->A mutations do not increase thromboembolic events in women

Cell Biology - Estrogen receptor isoforms function in endometrial carcinoma cells

Cervical Cancer - Cervical smear quality obtained by cervical cell sampler is comparable to cervix brush

Cervical Cancer - Human papillomavirus in organs of upper genital tract may indicate underlying infection

Cervical Cancer - Mitotic index and cyclin A may predict high-risk human papillomavirus infections

Cervical Cancer - Women with low literacy are less like to follow up with physicians after abnormal Pap smear

Chemotherapy - Advanced cancer patients safely treated with NV06, a novel isoflav-3-ene

Chondrosarcoma - Chondrosarcoma intrinsic radiation resistance linked to loss of p16(ink4a)

Chronic Myeloid Leukemia - Chronic myeloid leukemia linked to complex chromosomal rearrangements

Collaborations - Immunicon and AstraZeneca enter research and master services agreements

Colon Cancer - Colon cancer growth signals are repressed by prostaglandin dehydrogenase

Colon Cancer - Colon cancer risk is associated with body size and abdominal obesity

Colon Cancer - Colorectal cancer screening abnormal results associated with low follow-up rates

Colon Cancer - Metastatic gene transcription regulated in murine colorectal cancer cells

Colon Cancer - Researchers discover gene that may lead to drug for colon cancer prevention

Colorectal Cancer - Colorectal cancer distinguished by CpG island methylator phenotype

Colorectal Cancer - Colorectal cancer growth is fed by hypoxia-induced cyclooxygenase-2 production

Colorectal Cancer - Colorectal cancer linked to increased Bacteroides fragilis enterotoxin

Colorectal Cancer - Colorectal cancer postoperative wound healing enhanced by oxygen therapy

Colorectal Cancer - Colorectal cancer quantitative perfusion measurements by MDCT are reproducible

Colorectal Cancer - Colorectal cancer response to 5-FU predicted by tumor orotate phosphoribosyl transferase assay

Colorectal Cancer - Colorectal cancer risk linked to CHEK2 I157T

Colorectal Cancer - Colorectal cancer screening is a high-impact, cost-effective service

Colorectal Cancer - Colorectal cancer susceptibility linked to polymorphisms of CYP1A2 in Koreans

Colorectal Liver Metastases - Unilobar colorectal liver metastases recurrence reduced by portal vein embolization

Colorectal Mucinous Adenocarcinoma - Colorectal mucinous adenocarcinoma identified as a distinct subtype of colorectal cancer

Complementary & Alternative Medicine - Lung cancer metastasis inhibited by berberine

Complementary & Alternative Medicine - Theaflavin mixture from black tea was cytotoxic to cells from human oral cavity

DNA Research - Prostate cancer cells receive targeted therapy from monoclonal antibodies

DNA Research - Single mutations in cancer-related gene fragments acoustically discriminated

Dendritic Cell Vaccine - Infection of dendritic cells with vaccinia virus MVA reveals maturation-dependent cytopathogenicity

Developmental Biology - BRAF functions preferentially in extracellular matrix remodeling

Developmental Biology - Cell differentiation requires a protein kinase phosphorylation substrate

Diagnostics - Cancer angiogenesis can be assessed with selective integrin tracers

Diagnostics - Infotonics Center to develop prototype optical biopsy pill for Mediscience Technology

Diagnostics - Intra-articular fibroma of tendon sheath involved scapholunate and radiocarpal joints

Diagnostics - Reasons for poor outcomes and diagnoses of advanced stage cancer in indigenous Australians analyzed

Diagnostics - Small-bowel neuroendocrine tumor finds new diagnostics option in video capsule endoscopy

Diagnostics - Tumor contrast enhancement in low-field MRI improved without increasing contrast agent dose

Diet & Nutrition - Vitamin D may play a role in autoimmune diseases

Down Syndrome - Routine screening for celiac disease in children with Down Syndrome is costly and not always beneficial

Drug Delivery - Halozyme initiates Enhanze Technology trial

Drug Delivery - Low temperature sensitive liposome-doxorubicin may improve drug delivery to solid tumors

Drug Delivery - Sindbis viral vector enables gene-directed enzyme-prodrug therapy

Drug Development - 3-benzimidazol-2-yl-1H-indazoles identified as potent c-ABL inhibitors

Drug Development - Boronic-chalcone derivative shows promise as potent anticancer agent

Drug Development - Cancer angiogenesis and growth is targeted by new nonpeptidic topomimetics

Drug Development - CuraGen and TopoTarget initiate NCI-sponsored Phase I clinical trial of PXD101 and azacitidine

Drug Development - Enantioselective total synthesis of avrainvillamide and the stephacidins described

Drug Development - Human primary renal cells used as model for toxicity assessment of chemotherapeutic drugs

Drug Development - Novel class of cyclophosphamide prodrug developed

Drug Development - Novel FDG PET method to monitor tumor response during anticancer therapy described

Drug Development - Quigley compound QR-443 effective in preventing cachexia

Drug Development - Tumor vessels respond to orally active angiogenesis inhibitor YM-201627

Drug Resistance - Hypoxia induces 4-HPR resistance in leukemia cells

Endocrinology - Obesity related to hypothalamic tumor treatment is not due to leptin dysregulation

Endometrial Cancer - Endometrial cancer angiogenesis is linked to excess cyclooxygenase-2 production

Ependymoma - Ependymoma patients with MRI-detected metastasis do not benefit from CSF cytology

Esophageal Cancer - Advanced cancer of the esophagus and the gastroesophageal junction treatment discussed

Esophageal Cancer - Esophageal cancer clinical management affected by FDG-PET post-treatment assessment

Esophageal Cancer - Esophageal cancer patients receive implanted nasogastric feeding tube via ultrathin endoscope

Esophagogastric Adenocarcinoma - Esophagogastric adenocarcinoma patients experiencing anemia were treated with erythropoietin-alfa

Facilities - American Cancer Society moves international headquarters to downtown Atlanta

Finance - Allos Therapeutics reports loss of $0.13 per share

Finance - Cerus Corporation announces second quarter financial results

Finance - Dilon Technologies secures major financial deal

Finance - EDAP TMS S.A. closes private placement

Finance - Moffitt Cancer Center & Research Institute receives $25,000 grant from Armstrong Foundation

Finance - Onyx Pharmaceuticals reports second-quarter and six-month 2006 financial results

Finance - SGX Pharmaceuticals reports Q2 2006 cash at $47.7 million, up from $35.8 million in Q2 2005

Finance - Spectrum reports Q2 2006 net loss of $9 million compared to $4.6 million loss in Q2 2005

Finance - Sunesis Pharmaceuticals reports Q2 2006 revenues of $6.7 million, net loss of $4.5 million

Finance - Tapestry reports Q2 2006 operating loss of $4.4 million compared to $4.3 million a year ago

Finance - Telik reports $21.5 million net loss in Q2 2006 compared with $21 million in Q2 2005

Finance - Threshold reports Q2 2006 net loss of $15.5 million, up from $10.2 million a year ago

Finance - US Oncology reports Q2 2006 revenue of $689.4 million, $1,391.2 million for first 6 months

Gallbladder Cancer - Gallbladder cancer and cholangiocarcinoma staging aided by PET/CT

Gastric Cancer - BARF1 plays anti-apoptotic role in gastric cancer cells

Gastric Cancer - Gastric cancer and patient survival is predicted by CD105 quantification of angiogenesis

Gastric Cancer - Gastric cancer inhibited by gambogic acid

Gastric Cancer - Node-negative gastric cancer survival not improved after extended lymph node dissection

Gastrointestinal Stromal Tumors - Stomach gastrointestinal stromal tumor detected by gallium-67 scintigraphy

Gene Research - Researchers identify gene as protector of DNA, enemy of tumors

Genetics & Genomics - Basal hepatic and splenic iron status in mice is determined by multiple polymorphic loci

Glioma - Glioma malignancy should be evaluated by F-18-fluorodeoxyglucose

Glioma - Glioma outcome not significantly improved with addition of estramustine to radiotherapy

Glioma - Glioma patients responded to carboplatin and tamoxifen with response rates similar to other regimens

Glioma Vaccine - F98 glioma model is useful for studying mechanisms of glioma immunotherapy resistance

Glioneuronal Tumors - Rosette-forming glioneuronal tumor found in fourth ventricle of patient

HIV/AIDS Prevention - Scytovirin peptide displays potent anti-HIV activity

HIV/AIDS Therapy - Phase I study of interleukin-2 plus stem cell factor in HIV, cancer patients shows no advantages

Head & Neck Cancer - Elective N0 neck treatments should include levels II, III, and IV

Head & Neck Cancer - Fine needle aspiration biopsies performed by clinicians and cytopathologists are compared

Head & Neck Cancer - Head and neck cancer tumor vessels are targets of radioimmunotherapy

Head & Neck Cancer - Head and neck radiotherapy has some effects on free tissue transfer outcomes

Head & Neck Cancer - Level V lymph node dissection is not necessary in N+ necks below stage N2a

Head & Neck Cancer - Pyriform sinus carcinoma predictive factors for lymph node metastasis are determined

Head & Neck Cancer - Recurrent squamous cell carcinoma is treated with microsurgery and adjuvant radiotherapy

Head & Neck Cancer - Tongue cancers are more aggressive where endoglin is overexpressed

Healthcare Costs - Blue Cross chooses 15 projects to receive Prevention Minnesota funding

Healthcare Costs - Lower radical prostatectomy total hospital charges linked to high surgical volume

Hepatitis B & Hepatocellular Carcinoma - Hepatitis B DNA expression predicts outcome in hepatocellular carcinoma

Hepatitis B Virus - Hepatitis B persistence influences hepatocellular carcinoma methylation rate

Hepatitis C Therapy -  Agaricus blazei extract affects hepatitis C gene expression and viral load

Hepatocellular Carcinoma - Adeno-associated vectors do not contribute to liver tumor formation

Hepatocellular Carcinoma - Expression and immunogenicity of NY-ESO-1 clarified in hepatocellular carcinoma

Hepatocellular Carcinoma - Hepatocellular cancer and liver cirrhosis diagnosed by serum AsAGP concentration

Hepatocellular Carcinoma - Hepatocellular cancer tumor dissemination enhanced by chemokine receptor CCR7

Hepatocellular Carcinoma - Hepatocellular carcinoma linked to epigenetic silencing of NORE1B

Hepatocellular Carcinoma - Unresectable hepatocellular carcinoma survival predicted by quality of life

Hodgkin Lymphoma - Hodgkin lymphoma response monitoring by FDG-PET explained

Human Papillomavirus - DNA vaccine encoding HPV-16 E6 gene enhances antitumor activity

Human Papillomavirus - Smoking related to lower high-risk human papillomavirus clearance in HIV-negative women

Human Papillomavirus - Third Wave begins clinical trial for products to treat human papillomavirus

Human Papillomavirus - Vaccine targeting HPV 6, 11, 16, and 18 elicits long-lasting immune responses

Imaging - Brain tumor differentiation by MR imaging needs improvements

Imaging - Interventional breast sonography is best accomplished using conventional imaging

Immunology - Immunobiology of gestational trophoblastic diseases is reviewed

Intraocular Tumors - Intraocular tumors naturally eradicated by macrophages

Invasive Fungal Infection - Critically ill patients are predisposed to invasive fungal infections

Kaposi Sarcoma-Associated Herpesvirus - NF-kappa B activation by KSHV vFLIP required for spindle shape of infected endothelial cells

Kidney Cancer - Renal cell carcinomas are safely treated with percutaneous cryoablation

Laryngeal Cancer - Optical coherence tomography shows potential for laryngeal cancer diagnosis

Legal Issues - Community-oriented providers deliver on promise of Karon's Law

Leiomyoma - Leiomyoma of the nipple reported

Leukemia - BioCryst gets special protocol assessment from U.S. FDA for trial of Fodosine

Leukemia - Leukemia apoptosis sensitivity decreased by Fas phosphorylation

Leukemia - Leukemia cell differentiation linked to increase in zinc content

Leukemia - Leukemia cell survival enhanced by constitutive cyclooxygenase-2 expression

Leukemia - Leukemia decreased survival linked to pronormoblasts

Leukemia - Leukemia favorable outcome predicted by simplified flow cytometric assay

Leukemia - Leukemia patients previously treated with deoxycoformycin do not benefit from IFN-alpha therapy

Leukemia - Leukemia risk heightened due to high magnetic field exposure

Leukemia - Leukemia risk linked to MTHFR C677T polymorphism in Greek patients

Leukemia - Leukemia treated with geranylgeraniol generates cytochrome c-releasing factor 21

Licensing Agreements - Medical Discoveries, Eucodis sign agreement to develop topical steroidal breast cancer cream

Liver Cancer - A permissive environment plays a critical role in promoting progression and metastases of liver cancer

Liver Transplant - Liver transplant participant evaluation needs to be more effective and precise

Lobular Cancer - Lobular neoplasia might be precursor of invasive lobular carcinoma

Lung Cancer - Lung adenocarcinoma risk linked to OGG1-Ser326Cys polymorphism

Lung Cancer - Lung Cancer Alliance acknowledges first anniversary of Peter Jennings' death

Lung Cancer - Lung cancer linked to loss of MSH2 expression

Lung Cancer - Lung cancer patients palliated by paclitaxel, etoposide and carboplatin regimen

Lung Cancer - Lung cancer patients responded to front-line paclitaxel and topotecan chemotherapy

Lung Cancer - Lung cancer response rate not improved after adding mitomycin C to docetaxel

Lung Cancer - Lung cancer treated by administering pemetrexed immediately after gemcitabine as front-line therapy

Lung Cancer - Lung carcinogenesis might be linked to human papillomavirus infection

Lung Cancer - Lung tumor radiotherapy planning via 4DCT minimizes risk of normal tissue toxicity

Lung Cancer - Lung tumorigenesis found linked to Delta DNMT3B

Lung Cancer - Non-small cell lung cancer metastasis is marked by aminopeptidase N

Lung Cancer - Non-small cell lung cancer survival and response correlated with mismatch repair system status

Lung Cancer - Nonmalignant respiratory diseases may be independent risk factors for lung cancer

Lung Cancer - Nonsmall cell lung cancer risk linked to polymorphism in promoter of MDM2 gene

Lymphangioma - Periocular lymphangioma surgical outcome predicted by neuroimaging findings

Lymphoma - Angioimmunoblastic T cell lymphoma detected by PD-1 expression

Lymphoma - Lymphoma treatment with human soluble TRAIL/Apo2L warrants further study

MALT Lymphoma - Orbital MALT lymphoma treated by oral chlorambucil

Medical Errors - Medication errors affect children's leukemia treatment

Medulloblastoma - Medulloblastoma prognostication by anaplasia is uncertain

Melanocytic Tumors - Melanocytic tumors differentiated by distinct genetic alteration patterns

Melanoma - Dipeptide proline diphenyl phosphonates identified as inhibitors of seprase

Melanoma - Melanoma angiogenesis and metastasis is triggered when extracellular pH is lowered

Melanoma - Melanoma eyes analyzed for ocular surface alterations after proton beam radiation

Melanoma - Melanoma metastasis to the lungs may be prevented with anti-tissue factor gene therapy

Melanoma - Melanoma of the ear does not benefit from elective lymph node dissection

Melanoma - Melanoma treatment gene transfer improved by coreceptor

Melanoma Vaccine - Differentiation of melanoma-specific T cell responses is characterized with new approach

Meningioma - Chordoid meningioma characterized via clinicopathologic study of 12 cases

Meningioma - Meningioma patients did not benefit from salvage chemotherapy with irinotecan

Meningioma - Primary extradural meningioma patients should undergo resection of the dura to prevent recurrence

Mergers & Acquisitions - Registration statement for Infinity/Discovery Partners merger is now effective

Mergers & Acquisitions - Solos Endoscopy acquires early cancer detection products from Lifeline Biotechnologies

Merkel Cell Cancer - Merkel cell carcinoma survival improved in patients treated with surgery and radiotherapy

Multiple Myeloma Vaccine - Idiotype-specific immunotherapy in multiple myeloma is focus of review

Musculoskeletal Lesions - Musculoskeletal lesions accurately diagnosed by core needle biopsy

Nanotechnology - Researchers explore the use of nanotechnology as a diagnostic and treatment tool

Nasopharyngeal Carcinoma - Nasopharyngeal carcinoma genetic susceptibility linked to A870G cyclin D1 gene polymorphism

Natural Products - Argan oil may afford anti-atherogenic benefits

Natural Products - LB-18, derived from a marine sponge, induces apoptosis in neuroblastoma cells

Natural Products - New antitumor sesquiterpenoids isolated from Santalum album of Indian origin

Neuroendocrine Carcinoma - Large cell neuroendocrine carcinoma of the lung prognosis improved with chemotherapy

Non-Hodgkin Lymphoma - Cell Therapeutics announces encouraging pixantrone Phase III interim data

Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma patients responded to high-dose carmustine, etoposide, and cyclophosphamide

Non-Hodgkin Lymphoma - Non-Hodgkin lymphoma risk evaluated with nitrate and nitrite from drinking water and diet

Non-Hodgkin Lymphoma Prognostic - Natriuretic peptides reflect transient cardiac effect after high-dose cyclophosphamide

Non-Small Cell Lung Cancer - Avastin filed in Europe for treatment of most common form of lung cancer

Oncology - Cancer progresses when ubiquitin carrier protein destabilizes a key tumor suppressor

Oncology - Structured group exercise program is safe and well tolerated by adult cancer patients

Oncology - Tumor proliferation and angiogenesis reflect a time-dependent control of autoantibodies

Ontology - Ontological principles needed to bridge gap between medical and biological information

Osteosarcoma - Pediatric osteosarcoma clinical behavior predicted by histologic grade

Otorhinolaryngology - Cochlear implantation in postirradiated ears achieves good hearing outcomes

Otorhinolaryngology - Laser scanning microscopy is used to visualize ex vivo laryngeal epithelia

Ovarian Cancer - Elevated active mammalian target of rapamycin was found in postmenopausal ovarian endometriosis

Ovarian Cancer - Epithelial ovarian cancers with high ephrin B expression are more likely to recur

Ovarian Cancer - Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

Ovarian Cancer - Ovarian cancer ascites fluid harbors antiangiogenic fibrin products

Pain Management - Botulinum toxin A at a low concentration treats neuropathic pain after neck dissection

Pancreatic Adenocarcinoma - Pancreatic adenocarcinoma treated by 5-fluoruracil, leucovorin, epirubicin and carboplatin

Pancreatic Cancer - Pancreatic intraductal papillary mucinous neoplasm diagnosis is predictive of pancreatic neoplasia

Pancreatic Cancer - Pancreaticoduodenectomy is safe and has a low hospital mortality

Pancreatic Cancer - Threshold completes enrollment trials for treatment of pancreatic cancer

Pediatric Stem Cell Transplantation - Conversion from intravenous to oral cyclosporin A effective in pediatric stem cell transplant

Personnel - Celator Pharmaceuticals names Dr. Arthur C. Louie as new chief medical officer

Personnel - Dr. Jules Harris joins GlobeImmune scientific advisory board

Personnel - Janet Houghton, PhD, named chair of cancer biology at Cleveland Clinic

Personnel - Mesothelioma Applied Research Foundation names Vogelzang new board chair

Personnel - Oncologist Dr. Gerald Batist joins Chemokine's clinical advisory board

Pharmacogenomics - Pharmacogenomic study findings could aid decision-making in future leukemia clinical trials

Prostate Cancer - Diet changes, reinforced by stress management training, are effective in treating prostate cancer

Prostate Cancer - Postimplant dosimetry may not be necessary after real-time dynamic prostate brachytherapy

Prostate Cancer - Prostate cancer loss of a major regulatory protein signals the risk for metastasis

Prostate Cancer - Prostate cancer mimicked by distorted rectal tissue on prostate needle biopsy

Prostate Cancer - Prostate cancer patients find new hope in novel titanocene anti-cancer drugs

Prostate Cancer - Prostate cancer screening education needs to reach siblings of diagnosed patients

Prostate Cancer - Prostate cancer screening with PSATZ may reduce unnecessary biopsies

Prostate Cancer - Prostate cancer tumor volume was greater among African-Americans

Prostate Cancer - Prostate tumor progression and angiogenesis may be impeded by cyclooxygenase-2 blockade

Prostate Cancer - Prostate-specific antigen-targeted oncolytic adenovirus assessed

Prostate Cancer - Some prostate cancer patients are potentially overtreated

Proteomics - Antioncogenic kinase is regulated by an oncogenic phosphatase

Pulmonary Hamartoma - Pulmonary hamartoma development related to sex steroid hormone receptor expression

Radiotherapy - Presence or absence of tumor hypoxia is an important determinant in planning cancer therapy

Rectal Cancer - Rectal cancer preoperatively staged by 3D endorectal ultrasonography

Rectal Cancer - Study shows BSD's hyperthermia therapy plus chemo, radiation does not affect quality of life

Renal Cell Carcinoma - Renal cell carcinoma progression from neoplasia might be linked to increased COX-2 expression

Retroperitoneal Sarcoma - Retroperitoneal sarcoma treatment by combined-modality approaches discussed

Skeletal Disease - Skeletal disease's relationship to FGF23 warrants further study

Solid Tumors - Pediatric patients with solid tumors studied for maximum tolerated dose of irofulven

Stem Cell Research - CD34+ cord blood cells cultured with thrombopoietin accelerates platelet engraftment

Stem Cell Research - cDNA microarray evaluates gene expression in enriched hematopoietic stem cell populations

Stem Cell Research - Hematopoietic cell differentiation blocked by chimera

Stem Cell Transplantation - Early cytomegalovirus infection after stem cell transplantation monitored by PCR

Stem Cell Transplantation - Mesenchymal stromal cells may engraft in pediatric patients given bone marrow transplantation

Stem Cell Transplantation - Reduced intensity comparable to myeloablative stem cell transplantation in patients under 50

Stem Cell Transplantation - Stem cell transplant yields extended disease control and long-term survival in mantle cell lymphoma

Stomach Cancer - Risk of stomach cancer is not associated with dietary folate intake

Synovial Sarcoma - Synovial sarcoma is limited by the effects of sinomenine on interleukin-1 beta

Thyroid Cancer - Thyroid cancer major histocompatibility complex expression studied

Tonsillar Squamous Cell Carcinoma - Tonsillar squamous cell carcinoma treated by organ preservation therapy

Urothelial Cancer - Multifocal urothelial cancers examined by high throughput CGH array analysis

Uterine Cancer - Endometrial intraepithelial and uterine serous papillary carcinoma linked to GLUT1 expression

Uveal Melanoma - In uveal melanoma the iris resists new vessel growth after proton beam therapy

Uveal Melanoma - Uveal melanoma linked to chromosome 3 alterations

Vaccine Adjuvant - Mannosylated lipid core peptides in liposomes elicit strong immune responses with Quil A adjuvant

Vaccine Development - Interactions between peptides and heat shock protein 70 augment CD8+ T cell responses

Vaccine Research - Cancer vaccines emerge as novel therapies are developed and tested

Vascular Disease - Olympus and VisEn sign Japanese agreement for infrared fluorescence probes and imaging systems

Vestibular Schwannoma - Vestibular schwannoma treated best with stereotactic radiosurgery

Virology - Recombinant adenoviral vectors turn on the type I interferon system

Apoptosis - New findings from the United States, Singapore and United Kingdom in the area of apoptosis detailed

Apoptosis - Researchers from the United States and Italy publish new studies and findings in the area of apoptosis

Apoptosis - Researchers' data from the United States and Japan advance apoptosis research

Aspergillosis - Recent findings from the United States and France illuminate research in aspergillosis

Bladder Cancer - Research from Spain, Japan and Turkey in bladder cancer provides new insights

Blood Banks - Researchers from Spain, France and Italy publish new studies and findings in the area of blood banks

Breast Cancer - Data from Japan and the United States advance knowledge in breast cancer research

Breast Cancer - Findings from South Korea, United States and Italy advance knowledge in breast cancer research

Breast Cancer - Findings from the United States advance knowledge in breast cancer research

Breast Cancer - New findings from Italy and the United States in the area of breast cancer detailed

Breast Cancer - Recent studies from the United Kingdom, Germany and Canada add new data to breast cancer research

Breast Cancer - Research from Hungary, Sweden and the United States add new data to breast cancer body of knowledge

Breast Cancer - Researchers from Brazil, the United States and Japan report recent findings in breast cancer

Breast Cancer - Researchers from Japan, Greece and Belgium publish new studies and findings in the area of breast cancer

Breast Cancer - Researchers from Poland, the United Kingdom and Scotland provide details of new studies and findings in the area of breast cancer

Breast Cancer - Researchers from the United States, Italy and United Kingdom describe findings in breast cancer studies

Breast Cancer - Researchers' data from Germany, Japan and the South Korea advance breast cancer research

Breast Cancer - Researchers' work from the United States, Greece and Netherlands adds to breast cancer body of knowledge

Breast Cancer - Studies from the United States describe new findings in breast cancer research

Breast Cancer - Studies from the United States, Scotland and United Kingdom advance knowledge in breast cancer research

Cancer Research - Findings from South Korea and Australia in cancer provide new insights

Cancer Research - New findings from Canada, the People's Republic of China and the United States in the area of cancer described

Cancer Research - New findings in cancer described from the United States and Japan

Cancer Research - Research from Switzerland, Canada and the United States add new data to cancer body of knowledge

Cancer Research - Researchers from South Korea, Japan and People's Republic of China detail new studies and findings in the area of cancer

Cancer Research - Researchers' work from Singapore, Japan and the United States adds to cancer body of knowledge

Cancer Treatment - Findings from the People's Republic of China, United States and Germany advance knowledge in cancer treatment research

Cancer Treatment - Findings from the United Kingdom and United States in cancer treatment provide new insights

Cancer Treatment - Findings from the United States advance knowledge in cancer treatment research

Cancer Treatment - Findings from the United States, Egypt and Belgium describe new data in cancer treatment research

Cancer Treatment - New data from the United States and Canada lluminates research in cancer treatment

Cancer Treatment - New data from the United States and Norway lluminates research in cancer treatment

Cancer Treatment - New findings from France, the People's Republic of China and the Canada M5G 2M9; Email: amit in the area of cancer treatment detailed

Cancer Treatment - New findings from Germany, the People's Republic of China and the United States in the area of cancer treatment described

Cancer Treatment - New research from Italy, the United States and Japan in the area of cancer treatment detailed

Cancer Treatment - Recent findings from the People's Republic of China, United States and Belgium illuminate research in cancer treatment

Cancer Treatment - Reports from Austria, the United States and Germany advance knowledge in cancer treatment research

Cancer Treatment - Reports from the United States, People's Republic of China and United Kingdom add new data to cancer treatment research

Cancer Treatment - Research from the United States add new data to cancer treatment body of knowledge

Cancer Treatment - Researchers from Japan and the United States detail new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from South Korea and United States publish new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from the People's Republic of China and United States publish new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from the United Kingdom, United States and Canada report details of new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from the United States and Japan detail new studies and findings in the area of cancer treatment

Cancer Treatment - Researchers from the United States, People's Republic of China and Netherlands report recent findings in cancer treatment

Cancer Treatment - Researchers' data from France, Netherlands and Japan advance cancer treatment research

Cancer Treatment - Researchers' data from the United States, Japan and Italy advance cancer treatment research

Cancer Treatment - Researchers' work from the United States, Germany and Spain adds to cancer treatment body of knowledge

Cancer Treatment - Studies from the United Kingdom, Belgium and United States advance knowledge in cancer treatment research

Cell Biology - Reports from the People's Republic of China, Japan and United States describe recent advances in cell biology research

Cell Biology - Researchers from the United States, Iran and Belgium report details of new studies and findings in the area of cell biology

Cervical Cancer - Recent studies from the United States, Norway and Hungary add new data to cervical cancer research

Cervical Cancer - Research from the United States, United Kingdom and People's Republic of China add new data to cervical cancer body of knowledge

Cervical Cancer - Researchers' findings from the United States, South Korea and United Kingdom advance cervical cancer research

Colon Cancer - Researchers from Germany, Scotland and the United States detail new studies and findings in the area of colon cancer

Colon Cancer - Researchers from the United States and Italy publish new studies and findings in the area of colon cancer

Colorectal Cancer - Studies from Switzerland, Austria and Netherlands add new findings to colorectal cancer body of knowledge

Diet & Nutrition - Reports from South Korea, Japan and Germany add new data to diet & nutrition research

Gastric Cancer - Recent studies from Finland, Netherlands and the South Korea add new data to gastric cancer research

Gastric Cancer - Reports from Japan advance knowledge in gastric cancer research

Gastric Cancer - Researchers from the People's Republic of China and United States describe findings in gastric cancer studies

Gastric Cancer - Studies from Japan and Taiwan advance knowledge in gastric cancer research

Genetics - Reports from Brazil, the United States and Japan add new data to genetics research

Genetics - Research from the United States and Spain add new data to genetics body of knowledge

Genetics - Studies from the United States add new findings to genetics body of knowledge

Glioblastoma - New findings in glioblastoma described from Italy, the United States and Finland

Head & Neck Cancer - Findings from Australia, Canada and Finland in head & neck cancer provide new insights

Head & Neck Cancer - New findings from the United States and Italy in the area of head & neck cancer detailed

Head & Neck Cancer - New findings from the United States, Japan and Australia in the area of head & neck cancer described

Hepatocellular Carcinoma - Data from Japan and Taiwan advance knowledge in hepatocellular carcinoma research

Hepatocellular Carcinoma - Findings from Japan, the South Korea and Austria in hepatocellular carcinoma provide new insights

Hepatocellular Carcinoma - Researchers from the People's Republic of China, Japan and United States publish new studies and findings in the area of hepatocellular carcinoma

Hepatocellular Carcinoma - Researchers' data from Japan and Singapore advance hepatocellular carcinoma research

Hepatocellular Carcinoma - Researchers' findings from the United States and Singapore advance hepatocellular carcinoma research

Hepatocellular Carcinoma - Studies from the People's Republic of China and United States add new findings to hepatocellular carcinoma body of knowledge

Herpes - Data from the United States advance knowledge in herpes research

Herpes - Reports from Netherlands and United States advance knowledge in herpes research

Herpes - Researchers from the United States and Japan describe findings in herpes studies

Imaging - Recent studies from Taiwan, the United States and Canada add new data to imaging research

Imaging - Studies from the United States, Germany and Israel advance knowledge in imaging research

Leukemia - New data from the People's Republic of China, South Korea and Germany lluminates research in leukemia

Leukemia - Recent findings from Spain and the South Korea illuminate research in leukemia

Leukemia - Researchers from the United States and Switzerland provide details of new studies and findings in the area of leukemia

Leukemia - Researchers' work from Japan, France and the United States adds to leukemia body of knowledge

Leukemia - Studies from Canada, Germany and Sweden add new findings to leukemia body of knowledge

Lung Cancer - Findings from the United States, Japan and South Korea advance knowledge in lung cancer research

Lung Cancer - New findings from the United States and Japan in the area of lung cancer detailed

Lung Cancer - New findings in lung cancer described from Germany, France and the United States

Lung Cancer - New research from Japan and the United States in the area of lung cancer detailed

Lung Cancer - Recent studies from France and the United States add new data to lung cancer research

Lung Cancer - Recent studies from South Korea, Japan and Italy add new data to lung cancer research

Lung Cancer - Reports from Austria, France and Spain add new data to lung cancer research

Lung Cancer - Researchers from Japan and Austria report details of new studies and findings in the area of lung cancer

Lung Cancer - Researchers from Taiwan and Japan report details of new studies and findings in the area of lung cancer

Lung Cancer - Studies from Canada and Japan add new findings to lung cancer body of knowledge

Lung Cancer - Studies from Japan and the United Kingdom describe new findings in lung cancer research

Lymphoma - New findings in lymphoma described from Italy, Sweden and the United States

Lymphoma - Studies from Brazil, Germany and the United States describe new findings in lymphoma research

Lymphoma - Studies from the United States, Italy and United Kingdom add new findings to lymphoma body of knowledge

Melanoma - Findings from the United States and United Kingdom advance knowledge in melanoma research

Melanoma - Recent studies from Switzerland and the United States add new data to melanoma research

Melanoma - Reports from France, the United States and Italy advance knowledge in melanoma research

Neurology - Researchers from the United States provide details of new studies and findings in the area of neurology

Oncology - Researchers' data from the United States, France and Norway advance oncology research

Ovarian Cancer - Researchers from the United States, United Kingdom and Japan report recent findings in ovarian cancer

Pancreatic Cancer - Recent studies from Japan, the United States and the People's Republic of China add new data to pancreatic cancer research

Plague - Findings from the United States, India and France describe new data in plague research

Prostate Cancer - New data from the United States lluminates research in prostate cancer

Prostate Cancer - Recent findings from the United States illuminate research in prostate cancer

Prostate Cancer - Recent studies from the United States and United Kingdom add new data to prostate cancer research

Prostate Cancer - Researchers from the United States report details of new studies and findings in the area of prostate cancer

Prostate Cancer - Researchers from the United States, Canada and Germany describe findings in prostate cancer studies

Prostate Cancer - Researchers' data from Italy, the South Korea and the United Kingdom advance prostate cancer research

Prostate Cancer - Researchers' findings from the United States advance prostate cancer research

Prostate Cancer - Researchers' work from Chile, Turkey and Canada adds to prostate cancer body of knowledge

Prostate Cancer - Studies from Canada and Germany describe new findings in prostate cancer research

Radiotherapy - New research from Germany, Japan and the United States in the area of radiotherapy detailed

Renal Cancer - Recent findings from South Korea, Japan and Sweden illuminate research in renal cancer

Renal Cancer - Researchers from Germany and Spain detail new studies and findings in the area of renal cancer

Thyroid Cancer - Researchers' findings from the United States, Australia and Italy advance thyroid cancer research

Transplants - Recent studies from Germany, Taiwan and France add new data to transplants research

Transplants - Researchers from Turkey, Spain and the United States publish new studies and findings in the area of transplants

Transplants - Researchers' work from Italy, the United States and Greece adds to transplants body of knowledge

Vaccines - Recent findings in vaccines described by researchers from Sweden and Switzerland

Vaccines - Researchers from the United States publish new studies and findings in the area of vaccines

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