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Cancer Treatment

New research from Italy, the United States and Japan in the area of cancer treatment detailed

Published in Cancer Weekly, September 5th, 2006

Investigators in Italy, the United States and Japan have published new cancer treatment data.

Study 1: Timely DNA vaccine combined with systemic IL-12 prevents parotid carcinomas before a dominant-negative p53 makes their growth independent of HER-2/neu expression.

According to a study from Italy, "Double transgenic mice overexpressing the transforming rat HER-2/neu oncogene and the mutated p53, with both dominant-negative and a gain-of-function properties, display early aggressive and metastasizing parotid tumors. Multiple acinar and ductal hyperplasia foci overexpressing the HER-21neu gene product are evident at week 5 and progress to poorly...

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