Published in Cancer Weekly, September 12th, 2006
Study 1: Scientists have identified the human papillomavirus type 16 L1 surface loops required for neutralization by human sera.
Investigators in the United States report, "The variable surface loops on human papillomavirus (HPV) virions required for type-specific neutralization by human sera remain poorly defined. To determine which loops are required for neutralization, a series of hybrid virus-like particles (VLPs) were used to adsorb neutralizing activity from HPV type 16 (HPV16)-reactive human sera before being tested in an HPV16 pseudovirion neutralization...
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