Published in Cancer Weekly, September 19th, 2006
Study 1: Human telomerase reverse transcriptase elicited cytotoxic T cell responses in patients with hepatocellular carcinoma.
Scientists in Japan report, "Human telomerase reverse transcriptase, hTERT, has been identified as the catalytic enzyme required for telomere elongation. hTERT is expressed in most tumor cells but seldom expressed in most human adult cells. It has been reported that 80% to 90% of hepatocellular carcinomas (HCCs) express hTERT, making the enzyme a potential target in immunotherapy for HCC. In the current study, we identified hTERT-derived,...
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Source: Cancer Weekly (2006-09-19)
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