Umbilical Cord Blood
Expanded umbilical cord blood Treg cells resistant to immune suppressive agents
Published in Cancer Weekly, September 26th, 2006
"This study examines the effects of the most commonly used graft-versus-host disease (GVHD) prophylactic drugs on inducing apoptosis and suppressor cell function of human umbilical cord blood (UCB) CD4+25+ Treg and CD4+25- cells.
"Cyclosporin A (CSA), methylprednisolone (MP), methotrexate (MTX), and mycophenolic acid (MPA) were added to the final 6 days of expansion cultures of Treg or CD4+25- T-cells isolated from the same donor and each concurrently cultured under the same conditions," researchers in the United...
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Source: Cancer Weekly (2006-09-26)
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