Diagnostics

Shortening of T-1 leads to spoiled gradient-echo signal enhancement of image intensity

Published in Cancer Weekly, October 10th, 2006

The shortening of T-1 may lead to spoiled gradient-echo (SPGR) signal enhancement of image intensity.

"Enhancement of image intensity, using the T-1-weighted SPGR sequence, was measured in SCC tumor implanted in the flank of C3H mice while they were subjected to several types of oxygenation challenges inside a hyperbaric chamber designed and constructed to fit in an MRI resonator. The central portions of the tumor gave a positive enhancement, while the periphery showed signal reduction during both normobaric (NBO) and hyperbaric (HBO) oxygen challenges," scientists in the United States reported.

"In the contralateral normal leg, nearly 70% of the...

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Source: Cancer Weekly (2006-10-10)

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